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agonist

  1. D

    Glp1 future enhancing drug blocks mstn gene myostatin

    Skeletal muscle atrophy is defined as a reduction of muscle mass caused by excessive protein degradation. However, the development of therapeutic interventions is still in an early stage. Although glucagon‐like peptide‐1 receptor (GLP‐1R) agonists, such as exendin‐4 (Ex‐4) and dulaglutide, are...
    • darrenW29
    • Thread
    • addition agonist atrophic atrophy dulaglutide effect enhancing expression ex‐4 factors function glp‐1r increased injection kinase mass model mstn muscle myostatin myotubes protein signalling therapeutic treatment
    • Replies: 0
    • Forum: General Conversation Forum
  2. jimbosmith316

    Cabergoline - A Dopamine Agonist

    by Beverly M.K. Biller, M.D. The most interesting feature of cabergoline in terms of patient comphance is its extremely long half-life. Most patientscan be treated with a single weekly dose, is in contrast to the 1-3 times daily administration required for brornocriptine. Particularly in the...
    • jimbosmith316
    • Thread
    • agonist agonists amenorrhea bromocriptine cabergoline dopamine dose effective effects hyperprolactinemic levels normal patients pregnant prior prolactin side study therapy tolerated treated treatment tumor weekly women
    • Replies: 2
    • Forum: Steroids SARMS Peptides Forum
  3. drtbear1967

    Alpha-Yohimbine

    theguerillachemist A lot of people ask me what are the best legal fat burning supplements. While I still think that nothing rivals the ephedrine/caffeine stack, this compound is probably the best one that’s available in supplement form. Rauwolscine AKA alpha-yomhimbe is a yohimbine isomer that...
    • drtbear1967
    • Thread
    • 2-5mg adrenergic agonist alpha-2 alpha-yohimbine anxiety based binding burning caffeine compound doses effects fat great hips/thighs/abdominals human increases normal primatene receptors results running studies yohimbine
    • Replies: 0
    • Forum: Supplements Discussion
  4. drtbear1967

    New Fat Burning Compounds

    N-coumaryoldopamine and N-caffeoyldopamine are 2 very interesting fat-burning compounds. They are both beta-2 agonists(like ephedrine and clenbuterol) and have been shown to dramatically increase production of cyclic AMP(cAMP). Their mechanism of action is very similar to clenbuterol, which many...
    • drtbear1967
    • Thread
    • active agonist beta-2 bodybuilders breaks camp clenbuterol compounds dopamine dramatically enzyme fat fortunately green increase increases lypolysis research stimulants suggest taking tea temperature transferase
    • Replies: 2
    • Forum: Diet & Nutrition Forum
  5. Presser

    GHAR1NE Ibutamoren or MK677 selective agonist of ghrelin/growth hormone secretagogue

    Not a fan of secretagogues when you can administer the end result igf-1 directly, however its still one of the better secretagogues among its class and shows elevated igf-1 level in humans with just one dosage for nearly a full day, so below is a quick profile of mk-677 for anyone interested in...
    • Presser
    • Thread
    • agonist common cycle daily dosage elevated empty ghar1ne ghrelin/growth growth hormone hours humans ibutamoren igf-1 methylated mk-677 mk677 names oral secretagogue secretagogues selective unscheduled
    • Replies: 0
    • Forum: Steroids SARMS Peptides Forum
  6. D

    RAD-140: A SARM that actually has major effects & anabolic/androgenic ratio.

    RAD-140 is indeed very interesting. First, as to terminology. An “agonist” is a molecule which activates a receptor. A full agonist, at high enough concentration in the blood or test medium, can achieve 100% effect from the receptors. A partial agonist, also called a weak agonist, can only...
  7. akn

    RAD-140 – Finally a Worthwhile SARM?

    Q: “You’ve previously written that SARMs such as Ostarine are more hype than reality. They imitate the name of SERMs, claiming to be “Selective Androgen Receptor Modulators” to have a name that might go over better with the public than “anabolic steroids” does. Well you didn’t say exactly that...
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