dulaglutide
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More glp1 future to extreme muscle mass
Dulaglutide improved muscle strength and attenuated muscle loss in disuse condition. Ten-week-old C57BL/6 male mice were subjected to spiral wire immobilization for 4 d and administrated dulaglutide (Trulicity, 600 µg/kg, subscutaneous). Mice were maintained for additional 7 d. (A) Grip strength...- darrenW29
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- 0.001 0.01 analyses atrophy control data disuse-induced dulaglutide dulaglutide; expression glp-1 immobilization immunoblotting loading mrna muscle myostatin nf-κb protein quantification s.e.m shown treatment vehicle vehicle;
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- Forum: General Conversation Forum
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Glp1 future enhancing drug blocks mstn gene myostatin
Skeletal muscle atrophy is defined as a reduction of muscle mass caused by excessive protein degradation. However, the development of therapeutic interventions is still in an early stage. Although glucagon‐like peptide‐1 receptor (GLP‐1R) agonists, such as exendin‐4 (Ex‐4) and dulaglutide, are...- darrenW29
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- addition agonist atrophic atrophy dulaglutide effect enhancing expression ex‐4 factors function glp‐1r increased injection kinase mass model mstn muscle myostatin myotubes protein signalling therapeutic treatment
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- Forum: General Conversation Forum