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  1. D

    More glp1 future to extreme muscle mass

    Dulaglutide improved muscle strength and attenuated muscle loss in disuse condition. Ten-week-old C57BL/6 male mice were subjected to spiral wire immobilization for 4 d and administrated dulaglutide (Trulicity, 600 µg/kg, subscutaneous). Mice were maintained for additional 7 d. (A) Grip strength...
  2. D

    Glp1 future enhancing drug blocks mstn gene myostatin

    Skeletal muscle atrophy is defined as a reduction of muscle mass caused by excessive protein degradation. However, the development of therapeutic interventions is still in an early stage. Although glucagon‐like peptide‐1 receptor (GLP‐1R) agonists, such as exendin‐4 (Ex‐4) and dulaglutide, are...
  3. drtbear1967

    Eriobotrya Japonica extract(Loquat)

    Eriobotrya Japonica extract(Loquat) is a natural anabolic/anti-catabolic that work by manipulating certain genes that are responsible for processes like building/wasting muscle. Ursolic acid is one of the many bioacitves in Loquat that has been shown to increase muscle strength. Loquat activates...
  4. Presser

    Never Buy SYNTHETIC MADE IGF-1 LR3 -

    Recombinant Human LR3 Insulin-like Growth Factor-1 LR3-IGF1 Is What You Want To Purchase! Yes They are sold lyophilized as well as reconstituted straight from manufactors like Sigma and such. Stay away from The Synthetic garbage The Insulin-like growth factors (IGFs) are mitogenic...
  5. drtbear1967

    New Study on Lion's Mane

    theguerrillachemistA buddy of mine @ergogenic_health who knows a lot about botanicals and physiology sent me this study which is very interesting. Researchers gave mice Lion’s Mane extract(extracted in either ethanol or hexane) and measured its affect on PPAR delta(peroxisome...
  6. Presser

    Hyaluronic acid and Hypertrophy

    AbstractHyaluronic acid (HA) is a component of the extracellular matrix (ECM) in most vertebrate tissues and is thought to play a significant role during development, wound healing, and regeneration. In vitro studies have shown that HA enhances muscle progenitor cell recruitment and inhibits...
  7. Presser

    Hydronics H20 or Hyaluronic Acid

    AbstractSkin aging is a multifactorial process consisting of two distinct and independent mechanisms: intrinsic and extrinsic aging. Youthful skin retains its turgor, resilience and pliability, among others, due to its high content of water. Daily external injury, in addition to the normal...
  8. gandhisays

    Single dose testosterone increases total cholesterol levels and induces the expression of HMG CoA Reductase

    BackgroundCholesterol is mainly synthesised in liver and the rate-limiting step is the reduction of 3-hydroxy-3methylglutaryl coenzyme A (HMG-CoA) to mevalonate, a reaction catalysed by HMG-CoA reductase (HMGCR). There is a comprehensive body of evidence documenting that anabolic-androgenic...
  9. drtbear1967

    Androgen Receptors Explained

    Androgen Receptors Explained by Anthony Roberts One of the most peculiar things about the steroid community, and in particular, the online steroid community, is the ongoing level of misinformation about the androgen receptor and the...
  10. Presser

    Producing HGH hormone via E. coli

    Optimization of production of recombinant human growth hormone in Escherichia coli Background:Human growth hormone (hGH) is a single-chain polypeptide that participates in a wide range of biological functions such as metabolism of proteins, carbohydrates and lipids as well as in growth...
  11. Iron Game

    Benefits of Clenbuteral Build Muscle & Burn Fat at the Same Time

    Benefits of ClenbuteralBuild Muscle & Burn Fat at the Same Time Clenbuterol is a popular drug used by bodybuilders and athletes that belongs to a class of compounds known as beta-agonists that bind to the beta-adrenergic receptor embedded in the cell membrane— turning on cellular signaling...
  12. Iron Game

    GENE EXPRESSION IN TENDS/COLLAGEN AFTER HEAVY AAS USE

    GENE EXPRESSION IN TENDS/COLLAGEN AFTER HEAVY AAS USE Researchers in the European Journal of Applied Physiology examined how heavy use of the anabolic steroid Deca-Durabolin affected collagen strength in rats. The rats were separated into two groups: natural training and training with heavy...
  13. Presser

    insulin-like growth factors in the central nervous system. IGF-1 Lr3 Therapy Increases Neurons

    The role of the insulin-like growth factors in the central nervous system.D'Ercole AJ1, Ye P, Calikoglu AS, Gutierrez-Ospina G. Author information Abstract<abstracttext>Increasing evidence strongly supports a role for insulin-like growth factor-I (IGF-I) in central nervous system (CNS)...
  14. akn

    Does Estrogen Promote Muscle Growth? Part 2

    by Mike Arnold Most bodybuilders tend to view estrogen as a fat storage hormone, but its actions on adipose tissue are not so simple. In excessive amounts it can indeed lead to body fat acquisition, but in quantities compatible with male physiology it has a positive effect on bodyfat, making it...
  15. Iron Game

    How Exercise Changes Our DNA

    How Exercise Changes Our DNA<address class="byline author vcard" itemprop="author creator" itemtype="http://schema.org/Person" style="font-style: normal; display: inline-block; font-size: 0.6875rem; line-height: 0.75rem; font-weight: 700; font-family: nyt-cheltenham-sh, georgia, 'times new...
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