skeletal

CLENBUTEROL (FOR WEIGHT LOSS) What is Clenbuterol? The drug Clen, also referred to as Clenbuterol, is a bronchodilator and decongestant. It belongs to the 2-agonist class and is steroid-like but not a steroid. This medication widens and smooth’s the bronchial muscles, widening the airway...

NPB = MPS – MPBSo what does this equation mean? Net Protein Balance (skeletal muscle mass, for our purposes here) = Muscle Protein Synthesis – Muscle Protein Breakdown. Net protein balance (NPB) is defined as muscle protein synthesis (MPS) minus muscle protein breakdown (MPB), or NPB = MPS –...

A calorie surplus is obviously the main driver of a bulking phase, however, how large should this surplus be? A recent review by Slater et al. (2019) uncovered the energy costs associated with building muscle as well as the metabolic adaptations that occur during high calorie dieting plus lean...

What To Do When Cutting Calories Becomes Too Hard We all get to that point in our diet when cutting calories more becomes too much of a burden. THAT’S when we like to add in some cardio. Here’s why we suggest HIIT Cardio to be a great option. High-Intensity Interval training (HIIT)...

The length-tension relationship of skeletal muscle is well-known; however, scientists and fitness professionals rarely realize its relevance to muscle growth. We know that mechanical tension is the main stimulus for muscle growth and the length-tension curve shows us that muscle fibers...

Muscle in a bottle? Your secret strength-building weapon could be sitting in your medicine cabinet. Upping your intake of vitamin D may help you maintain stronger muscles, says recent research published in the journal Medicine & Science in Sports & Exercise. Researchers examined 419 adults (20...

theguerrillachemistA buddy of mine @ergogenic_health who knows a lot about botanicals and physiology sent me this study which is very interesting. Researchers gave mice Lion’s Mane extract(extracted in either ethanol or hexane) and measured its affect on PPAR delta(peroxisome...

European Journal of Applied Physiology April 2019, Volume 119, Issue 4, pp 825–839 | Cite as Mechanisms of vitamin D on skeletal muscle function: oxidative stress, energy metabolism and anabolic state Authors Authors and affiliations Katarzyna Patrycja DzikJan Jacek KaczorEmail author This...

What To Do When Cutting Calories Becomes Too Hard We all get to that point in our diet when cutting calories more becomes too much of a burden. THAT’S when we like to add in some cardio. Here’s why we suggest HIIT Cardio to be a great option. High-Intensity Interval training...

IGF 1 Study and Conclusion Below is pretty amazing, and puzzles the the scientists as to how its possible to add more muscle mass without adding anymore food intake, but rather just by adding in IGF 1 or IGF 1 lr3, and also greater utilization of carbs. Pretty awesome stuff man! A main...

AbstractHyaluronic acid (HA) is a component of the extracellular matrix (ECM) in most vertebrate tissues and is thought to play a significant role during development, wound healing, and regeneration. In vitro studies have shown that HA enhances muscle progenitor cell recruitment and inhibits...

Im sure that title caught your eye and many are probably thinking “I don’t have ED so why would anyone take cialis for bodybuilding?” Well, surprisingly enough, cialis or tadalafil, holds some merit when it comes to improving physique development. Tadalafil is a PDE-5 (phosphodiesterase type 5...

theguerillachemist This is one of my favorite "prosteroid" compounds from the early 2000s. Desoxymethyltestoserone, AKA Madol and Pheraplex, is an active anabolic steroid that was introduced to the market in 2005 by Patrick Arnold...suprise surprise lol. Structurally, Madol is a very...

Androgen Receptors Explained by Anthony Roberts One of the most peculiar things about the steroid community, and in particular, the online steroid community, is the ongoing level of misinformation about the androgen receptor and the...

WHEY PROTEIN 44 - 2LBS Human Whey 44® is for people wanting to experience significant growth! Our bodies are constantly growing and rebuilding. Adding Human Whey 44 gives your body that extra true protein. Human Whey 44® can be used as: A meal replacement To tone and strengthen muscle...

Insulin-like growth factor-1 builds muscle (hypertrophy) and utilizes carbohydrates as fuel for energy. We characterized the metabolic profile of transgenic mice exhibiting enhanced muscle mass driven by increased mIGF-1 expression (MLC/mIGF-1). As expected, 6-month-old MLC/mIGF-1 mice were...

Benefits of ClenbuteralBuild Muscle & Burn Fat at the Same Time Clenbuterol is a popular drug used by bodybuilders and athletes that belongs to a class of compounds known as beta-agonists that bind to the beta-adrenergic receptor embedded in the cell membrane— turning on cellular signaling...

While injecting test increases protein synthesis by roughly 50 times, depending on dose and time, most bodybuilders forget that it will reduce collagen synthesis by more than 50% -- more like 80%, giving you the collagen synthesis rate of a senior citizen. Since collagen makes up tendons, bros...

Alpha-ketoglutarate promotes skeletal muscle hypertrophy and protein synthesis through Akt/mTOR signaling pathways.Cai X1, Zhu C1, Xu Y1, Jing Y1, Yuan Y1, Wang L1, Wang S1, Zhu X1, Gao P1, Zhang Y1, Jiang Q1,2, Shu G1,2. Author information Abstract<abstracttext>Skeletal muscle weight loss is...

Although building muscle without exercise may seem like the ideal endpoint of all anabolic research, this is a feat that just hasn’t been realized yet. There are a number of effective drugs and supplements for augmenting muscle growth, but resistance training is in inseparable part to the...