Growth Hormone Releasing Peptide (GHRP-6) is a peptide in the growth factor family. It has strong effect on the release of Human Growth Hormone (HGH) in a specific and dose-related manner. GHRP can be effectively used in the treatment of growth hormone (GH) deficiency. Growth hormone releasing hexapeptide works by signaling the pituitary gland to begin growth hormone secretion.
Increased GH and IGF-1 levels are desirable for those looking to improve physique. Human growth hormone has been known to enhance immune response and stimulate the immune system, particularly older subjects. Dosed at night for anti-aging purposes and multiple times throughout the day for anabolism. GHRP is often used in conjunction with GHRH cjc-1295 to amplify growth hormone pulse. Avoid fats and carbohydrate a half hour on each side of dosing GHRP-6.
Bodybuilders and athletes utilize GHRP in an effort to build more muscle and burn fat. Some GHRP-6 users include it in their post cycle therapy (PCT). Cycling GHRP-6 in the off weeks from IGF/GH cycles is also becoming prevalent. Researchers wish to kick-start their body into producing their own natural GH & IGF, while gaining as if they remained on the GH/IGF peptides.
GHRP-6's main use is to promote food intake by stimulating hunger and aid in energy metabolism. The major side effect being a significant increase in appetite due to a stimulating the release of Ghrelin (about 20 minutes post injection), a hormone released naturally in the lining of the stomach and increases hunger and gastric emptying. This is why GHRP-6 can be used in the treatment of cachexia (wasting), eating disorders and obesity.
Benefits of increased HGH levels through GHRP-6 stimulation include: an increase in strength, muscle mass and body fat loss, rejuvenation and strengthening of joints, connective tissue and bone mass. Enhanced HGH secretion also leads to the liver secreting more IGF-1, which is thought to be the primary anabolic mechanism of action for Growth Hormone.
GHRP-6 5MG Peptide:
Mixing: Bacteriostatic water is used for reconstitution. When diluted, peptide lasts a very long time when left alone in the refrigerator (months)
Example- 2.5ml(cc) bacteriostatic water per 5mg GHRP vial equates to a 100mcg dose approximately each 2-3 marks on a U100 insulin syringe.
Example- 5ml(cc) bacteriostatic water per 5mg GHRP vial equates to a 100mcg dose approximately every 5 marks on a U100 insulin syringe.
Dosing: The saturation dose of GHRP-6 has been determined to be around 100mcg. More is not better in regards to this secretalogue
5mg GHRP = 5,000mcg
5,000mcg/100mcg = 50 100mcg GHRP doses per 5mg
GHRP-6 may be the most cost effective growth peptide available.
Insulin-like Growth Factor LR3 (IGF-1)
IGF-1 (Long R3 IGF-1) Dose:
Light: 25 mcg
Common: 50 mcg
Large: 100 mcg
IGF-1 is administered for one month, give or take a week.
Insulin-like Growth Factor (Long-R3 IGF-1), an 83 amino acid analog of IGF-1 is a highly anabolic hormone released primarily in the liver with the stimulus of growth hormone (HGH).
IGF-1 is the most potent growth factor found in the body and causes muscle cell hyperplasisa.
Freeze dried (lyophilized) IGF-1 (in powder state) should be stored in the freezer (-18 degrees celsius).
Dilute the IGF-1 peptide with 2mls of Acetic Acid (.6%). Assuming (*DO NOT ASSUME*) Acetic Acid (AA) will yield the correct pH balance of your research peptide.
Note: This creates a concentration of 500mcg/ml. So each 1/10 of a ML is 50mcg***8217;s.
Draw the desired amount of IGF in to a syringe. Desired amount should be the approx dosage wanted.
Example- 2mls AA used to reconstitute IGF-1 1mg vial means 5 units on a U100 insulin syringe would equal 25mcg IGF-1 LR3
Pre-load your syringes at 5iu (25mcg IGF-1). Divide your IGF-1 into 40 syringes for storage in the freezer.
Thaw prior to administration. Draw from your NaCL after thawed to buffer (.5ml is enough).
Unknown whether injecting IGF-1 to increase muscle growth is efficacious. Many believe in the value of this powerful growth factor. Question currently is whether IGF-1 is effective when not manufactured by the tissues themselves.
It is possible to go into hypoglycemia fro IGF-1 supplementation. Effect is dose dependant.
Hexarelin
by Anthony Roberts - Hexarelin (HEX) is a peptide GH secretagogue, structurally similar to GHRP-6, in the growth factor family which stimulates the release of growth hormone (GH). It can be used medically to treat GH deficiency.
Background
Although relatively new, Hexarelin is becoming a popular choice as a performance enhancement drug. Hexarelin is currently available from several research companies.
Action
Due to Hexarelin's ability to increase secretion of natural Growth Hormone, most of its effects are similar to those of synthetic GH, although to a slightly lesser extent. Effects of its use include: increase in strength, growth of new muscle fibers, increase in the size of already existing muscle fibers, neural protection, joint rejuvenation, protection and healing. Also, the GH receptors in adipose (fat) tissue allow for potential fat reduction with Hexarelin use. The increase of circulating GH through Hexarelin use causes levels of Insulin-Like Growth Factor (IGF-1) to rise in the liver. IGF-1 is the prime cause of muscle growth in response to GH stimulation.
There is no appetite boost with Hexarelin use (as opposed to GHRP-6***8217;s extreme appetite increase) due to its inability to drastically increase Ghrelin levels that are responsible for added hunger and quicker gastric emptying.
Technical Data
In studies where Hexarelin was injected subcutaneously, Growth Hormone, measured through plasma concentrations, increased significantly and within thirty minutes of injection. GH levels decreased back to normal around four hours post injection (1). The GH increase, has been found to be effective up to 2mg/kg, any further increase in dose was found to be ineffective in causing a GH response (2).
Results showed that Hexarelin's effect on GH stimulation tapered between weeks 4 through 16. Separating cycles by 4 week off periods, avoided the negative feedback loop and the next cycle of Hexarelin produced the same level of results as the first cycle (3).
User Notes
I used Hexarelin awhile back, at a dose of about 200mcg/day, and found it to be very good for healing my injuries, burning a bit of fat, and helped me gain a bit of muscle.
I also have a couple of friends who are powerlifters, and they were able to use Hexarelin to heal an old Pec injury and train pain free while on it. My bodybuilder friends (yes, not only do I have friends, but some are actually bodybuilders) have said that 400 mcg/day of Hexarelin gave them similar results to low doses of GH (maybe 1-2 iu/day would be a good equivalent).
Overall, Hexarelin is a good all purpose anabolic. Also, since we know that IGF and GH use produces a shutdown of your endogenous levels of those hormones, Hexarelin also seems very useful for ***8220;GH-PCT***8221; or ***8220;IGF-PCT***8221;, as it can help restore your natural levels of those hormones after a cycle of them.
References
Imbimbo, B.P., et. al Growth hormone-releasing activity of hexarelin in humans. A dose-response study.Eur J Clin Pharmacol. 1994;46(5):421-5.
Imbimbo, B.P., et. al Growth hormone-releasing activity of hexarelin in humans. A dose-response study.Eur J Clin Pharmacol. 1994;46(5):421-5.
Rahim, A., Shalet, SM Does desensitization to hexarelin occur? Growth Horm IGF Res. 1998 Apr;8 Suppl B:141-3
Bremelanotide (PT-141)
Bremelanotide PT-141 Dose:
Light: .5mg
Common: 1mg
Large: 2mg
Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II). PT-141 is a metabolite of melanocyte stimulating hormone that targets desire.
Treatment: PT-141 is the only synthetic aphrodisiac. The aphrodisiac effects of Bremelanotide are in a class of its own. Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Nine out of ten volunteers experienced sexual arousal in clinical trials. Unlike Viagra and other related medications (PDE5s - blood pushers), PT-141 acts upon the nervous system. Viagra, Cials and Levitra are not considered aphrodisiacs as they do not have any direct effect on the libido. However, treatment with PDE5 inhibitors and PT-141 have known synergy.
Men's Journal Magazine: ...it took hold. I felt a great surge of affection (greater than any regular level of arousal). My body tingled and I developed an erection that wouldn***8217;t quit. For two hours the drug wouldn***8217;t let me out of its grasp ***8212; nor my wife out of mine. -Frederick Kaufman
Females: Women who took part in trials said that they felt a "tingling and a throbbing" along with "a strong desire to have sex." An initial flush occurs post injection, followed by nausea which is dose dependent. For most, effects generally do not take place until a couple hours post injection, peaking around the four hour mark. Men said PT-141 made them feel "younger and more energetic" as well as sexually interested and aroused. "You're ready to take your pants off and go," said user "a drug that makes you not only able to but eager to."
Bremelanotide PT-141 Peptide: Bremelanotide comes in 10mg vials. As a lifestyle peptide, the 10mg product is a lot to consume and may offer up to 20 doses when dosing light. The PT-141 peptide reconstituted with bacteriostatic water remains potent in the fridge for months.
Window of Opportunity: Bremelanotide, injected (subcutaneously), has a unique window of opportunity lasting six to 72 hours. In lab trials female rats exposed to PT-141 began "flirting" with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood. The human PT-141 date is one where the dosage precedes the activity by at least a couple hours. When the stars align, hours after the injection, ...this is your window of opportunity, enjoy.
Mixing: Bacteriostatic water is used for reconstitution.
Example- 1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
Example- 1ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 50 units on a U100 insulin syringe.
Recommended strategy for mixing and dosing would be to reconstitute with the volume that yields a .1ml injection.
Example- 1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
Example- .2ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 10 units on a U100 insulin syringe.
Dosing: Read as much as possible to gain clarity and align expectations. Gradually dosing increases likelihood for success without sides. A test dose of .25-.5mg on the first attempt is recommended. 1mg, give or take a quarter, is the efficacious dose which yields the most positive reports by users.
Melanotan One (MT-1)
Afamelanotide (M-I) Dose:
Light: .5mg
Common: 1mg
Large: 2mg Melanotan/Afamelanotide synthetic melanocyte stimulating hormone (a-MSH) induces skin pigmentation through melanogenisis, melanin production. Melanin prevents cellular damage in the skin by absorbing, reflecting and refracting light. Melanotan reduces sun damage to UV exposed skin transforming cells to produce dark protective melanin.
Melanotan Results: Melanotan favors production of eumelanin (black/brown) over pheomelanin pigment. Injecting this linear amino acid Melanotan 1 peptide offers super-physiological levels of tanning ability.
Research Use: The half-life of Melanotan peptides is very brief. Afamelanotide is being developed in implant form for the ease of use in dermatology. The implant contains a controlled release effecting melanin density for months. Melanotan One is offered in research peptide form (Melanotan).
Lifestyle: Melanocortins have the potential to be the next big thing in lifestyle cosmetic treatment (Viagra, Botox, etc). Melanotan can be appropriately used continuously as well as intermittently.
Recommended Therapy: Intermittent therapy, lasting 10 days (skin type III) to 6 months (skin type I) works well. Take note how long after your Melanotan administration melanin density stays elevated.
Peptide Molecule: Two amino acids present in the bodies natural a-MSH have been changed in production of Melanotan 1 increasing stablity. Melanotan only works when injected subcutaneously.
Amino acid sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Clinical Trial: Melanotan is still undergoing clinical trials and has not reached approved status. People use on the pretenses and understanding that it is for research purposes only. Users may suffer from slight nausea and flushing after subcutaneous injection; however it is reported to be mild and pass quickly.
Administration of Research Melanotan
Safe and controlled administration of Afamelanotide for research is done much like that of Melanotan 2. Melanotan One offered as a peptide in a multi-dose sterile vial is desirable. Implants, nasal sprays and pills are not applicable/efficacious at the present time.
Melanotan One is less efficacious than its counterpart Melanotan 2 for achieving a dark tan. Afamelanotide will therefore require 8-10x the dosage to see comparable results. Melanotan One users want minimum side and peripheral effects with a focus on photoprotection. Be patient and prepared through your Melanotan journey.
Melanotan Treatment: Dosing According to Skin Type
Fitzpatrick Skin Type I: 1mg-2mg/day. 100mg total may be necessary to achieve desired color. UV exposure after at least 20mg in system
Fitzpatrick Skin Type II: .75mg-1.5mg/day. 60mg should be sufficient to get color. UV exposure after 10-20mg
Fitzpatrick Skin Type III: .5mg-1mg/day. A sunless tan may be realistic
Fitzpatrick Skin Type IV: Do not use Melanotan
Melanotan Video from Australia
Melanotan can assist the develop a protective tan in users. A natural tan is developed in response to cell damage caused by UV radiation. Ultraviolet rays penetrate the upper layers of the skin, triggering a-MSH, stimulating melanin production. Melanin deposits act as a natural sunblock at the cellular level. Melanotan tanning injections may offer a way to bring upon a safe, cosmetic tan with less damage.
Increased GH and IGF-1 levels are desirable for those looking to improve physique. Human growth hormone has been known to enhance immune response and stimulate the immune system, particularly older subjects. Dosed at night for anti-aging purposes and multiple times throughout the day for anabolism. GHRP is often used in conjunction with GHRH cjc-1295 to amplify growth hormone pulse. Avoid fats and carbohydrate a half hour on each side of dosing GHRP-6.
Bodybuilders and athletes utilize GHRP in an effort to build more muscle and burn fat. Some GHRP-6 users include it in their post cycle therapy (PCT). Cycling GHRP-6 in the off weeks from IGF/GH cycles is also becoming prevalent. Researchers wish to kick-start their body into producing their own natural GH & IGF, while gaining as if they remained on the GH/IGF peptides.
GHRP-6's main use is to promote food intake by stimulating hunger and aid in energy metabolism. The major side effect being a significant increase in appetite due to a stimulating the release of Ghrelin (about 20 minutes post injection), a hormone released naturally in the lining of the stomach and increases hunger and gastric emptying. This is why GHRP-6 can be used in the treatment of cachexia (wasting), eating disorders and obesity.
Benefits of increased HGH levels through GHRP-6 stimulation include: an increase in strength, muscle mass and body fat loss, rejuvenation and strengthening of joints, connective tissue and bone mass. Enhanced HGH secretion also leads to the liver secreting more IGF-1, which is thought to be the primary anabolic mechanism of action for Growth Hormone.
GHRP-6 5MG Peptide:
Mixing: Bacteriostatic water is used for reconstitution. When diluted, peptide lasts a very long time when left alone in the refrigerator (months)
Example- 2.5ml(cc) bacteriostatic water per 5mg GHRP vial equates to a 100mcg dose approximately each 2-3 marks on a U100 insulin syringe.
Example- 5ml(cc) bacteriostatic water per 5mg GHRP vial equates to a 100mcg dose approximately every 5 marks on a U100 insulin syringe.
Dosing: The saturation dose of GHRP-6 has been determined to be around 100mcg. More is not better in regards to this secretalogue
5mg GHRP = 5,000mcg
5,000mcg/100mcg = 50 100mcg GHRP doses per 5mg
GHRP-6 may be the most cost effective growth peptide available.
Insulin-like Growth Factor LR3 (IGF-1)
IGF-1 (Long R3 IGF-1) Dose:
Light: 25 mcg
Common: 50 mcg
Large: 100 mcg
IGF-1 is administered for one month, give or take a week.
Insulin-like Growth Factor (Long-R3 IGF-1), an 83 amino acid analog of IGF-1 is a highly anabolic hormone released primarily in the liver with the stimulus of growth hormone (HGH).
IGF-1 is the most potent growth factor found in the body and causes muscle cell hyperplasisa.
Freeze dried (lyophilized) IGF-1 (in powder state) should be stored in the freezer (-18 degrees celsius).
Dilute the IGF-1 peptide with 2mls of Acetic Acid (.6%). Assuming (*DO NOT ASSUME*) Acetic Acid (AA) will yield the correct pH balance of your research peptide.
Note: This creates a concentration of 500mcg/ml. So each 1/10 of a ML is 50mcg***8217;s.
Draw the desired amount of IGF in to a syringe. Desired amount should be the approx dosage wanted.
Example- 2mls AA used to reconstitute IGF-1 1mg vial means 5 units on a U100 insulin syringe would equal 25mcg IGF-1 LR3
Pre-load your syringes at 5iu (25mcg IGF-1). Divide your IGF-1 into 40 syringes for storage in the freezer.
Thaw prior to administration. Draw from your NaCL after thawed to buffer (.5ml is enough).
Unknown whether injecting IGF-1 to increase muscle growth is efficacious. Many believe in the value of this powerful growth factor. Question currently is whether IGF-1 is effective when not manufactured by the tissues themselves.
It is possible to go into hypoglycemia fro IGF-1 supplementation. Effect is dose dependant.
Hexarelin
by Anthony Roberts - Hexarelin (HEX) is a peptide GH secretagogue, structurally similar to GHRP-6, in the growth factor family which stimulates the release of growth hormone (GH). It can be used medically to treat GH deficiency.
Background
Although relatively new, Hexarelin is becoming a popular choice as a performance enhancement drug. Hexarelin is currently available from several research companies.
Action
Due to Hexarelin's ability to increase secretion of natural Growth Hormone, most of its effects are similar to those of synthetic GH, although to a slightly lesser extent. Effects of its use include: increase in strength, growth of new muscle fibers, increase in the size of already existing muscle fibers, neural protection, joint rejuvenation, protection and healing. Also, the GH receptors in adipose (fat) tissue allow for potential fat reduction with Hexarelin use. The increase of circulating GH through Hexarelin use causes levels of Insulin-Like Growth Factor (IGF-1) to rise in the liver. IGF-1 is the prime cause of muscle growth in response to GH stimulation.
There is no appetite boost with Hexarelin use (as opposed to GHRP-6***8217;s extreme appetite increase) due to its inability to drastically increase Ghrelin levels that are responsible for added hunger and quicker gastric emptying.
Technical Data
In studies where Hexarelin was injected subcutaneously, Growth Hormone, measured through plasma concentrations, increased significantly and within thirty minutes of injection. GH levels decreased back to normal around four hours post injection (1). The GH increase, has been found to be effective up to 2mg/kg, any further increase in dose was found to be ineffective in causing a GH response (2).
Results showed that Hexarelin's effect on GH stimulation tapered between weeks 4 through 16. Separating cycles by 4 week off periods, avoided the negative feedback loop and the next cycle of Hexarelin produced the same level of results as the first cycle (3).
User Notes
I used Hexarelin awhile back, at a dose of about 200mcg/day, and found it to be very good for healing my injuries, burning a bit of fat, and helped me gain a bit of muscle.
I also have a couple of friends who are powerlifters, and they were able to use Hexarelin to heal an old Pec injury and train pain free while on it. My bodybuilder friends (yes, not only do I have friends, but some are actually bodybuilders) have said that 400 mcg/day of Hexarelin gave them similar results to low doses of GH (maybe 1-2 iu/day would be a good equivalent).
Overall, Hexarelin is a good all purpose anabolic. Also, since we know that IGF and GH use produces a shutdown of your endogenous levels of those hormones, Hexarelin also seems very useful for ***8220;GH-PCT***8221; or ***8220;IGF-PCT***8221;, as it can help restore your natural levels of those hormones after a cycle of them.
References
Imbimbo, B.P., et. al Growth hormone-releasing activity of hexarelin in humans. A dose-response study.Eur J Clin Pharmacol. 1994;46(5):421-5.
Imbimbo, B.P., et. al Growth hormone-releasing activity of hexarelin in humans. A dose-response study.Eur J Clin Pharmacol. 1994;46(5):421-5.
Rahim, A., Shalet, SM Does desensitization to hexarelin occur? Growth Horm IGF Res. 1998 Apr;8 Suppl B:141-3
Bremelanotide (PT-141)
Bremelanotide PT-141 Dose:
Light: .5mg
Common: 1mg
Large: 2mg
Bremelanotide (PT-141) was developed from Melanotan 2 (MT-II). PT-141 is a metabolite of melanocyte stimulating hormone that targets desire.
Treatment: PT-141 is the only synthetic aphrodisiac. The aphrodisiac effects of Bremelanotide are in a class of its own. Studies have shown Bremelanotide to be effective in treating sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). Nine out of ten volunteers experienced sexual arousal in clinical trials. Unlike Viagra and other related medications (PDE5s - blood pushers), PT-141 acts upon the nervous system. Viagra, Cials and Levitra are not considered aphrodisiacs as they do not have any direct effect on the libido. However, treatment with PDE5 inhibitors and PT-141 have known synergy.
Men's Journal Magazine: ...it took hold. I felt a great surge of affection (greater than any regular level of arousal). My body tingled and I developed an erection that wouldn***8217;t quit. For two hours the drug wouldn***8217;t let me out of its grasp ***8212; nor my wife out of mine. -Frederick Kaufman
Females: Women who took part in trials said that they felt a "tingling and a throbbing" along with "a strong desire to have sex." An initial flush occurs post injection, followed by nausea which is dose dependent. For most, effects generally do not take place until a couple hours post injection, peaking around the four hour mark. Men said PT-141 made them feel "younger and more energetic" as well as sexually interested and aroused. "You're ready to take your pants off and go," said user "a drug that makes you not only able to but eager to."
Bremelanotide PT-141 Peptide: Bremelanotide comes in 10mg vials. As a lifestyle peptide, the 10mg product is a lot to consume and may offer up to 20 doses when dosing light. The PT-141 peptide reconstituted with bacteriostatic water remains potent in the fridge for months.
Window of Opportunity: Bremelanotide, injected (subcutaneously), has a unique window of opportunity lasting six to 72 hours. In lab trials female rats exposed to PT-141 began "flirting" with male rats for sex. Postures and movements left no doubt in the male rats minds that they were in the mood. The human PT-141 date is one where the dosage precedes the activity by at least a couple hours. When the stars align, hours after the injection, ...this is your window of opportunity, enjoy.
Mixing: Bacteriostatic water is used for reconstitution.
Example- 1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
Example- 1ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 50 units on a U100 insulin syringe.
Recommended strategy for mixing and dosing would be to reconstitute with the volume that yields a .1ml injection.
Example- 1ml(cc) bacteriostatic water per 10mg PT-141 vial equates to a 1mg dose approximately each 10 units on a U100 insulin syringe.
Example- .2ml(cc) bacteriostatic water per 2mg PT-141 vial equates to a 1mg dose approximately every 10 units on a U100 insulin syringe.
Dosing: Read as much as possible to gain clarity and align expectations. Gradually dosing increases likelihood for success without sides. A test dose of .25-.5mg on the first attempt is recommended. 1mg, give or take a quarter, is the efficacious dose which yields the most positive reports by users.
Melanotan One (MT-1)
Afamelanotide (M-I) Dose:
Light: .5mg
Common: 1mg
Large: 2mg Melanotan/Afamelanotide synthetic melanocyte stimulating hormone (a-MSH) induces skin pigmentation through melanogenisis, melanin production. Melanin prevents cellular damage in the skin by absorbing, reflecting and refracting light. Melanotan reduces sun damage to UV exposed skin transforming cells to produce dark protective melanin.
Melanotan Results: Melanotan favors production of eumelanin (black/brown) over pheomelanin pigment. Injecting this linear amino acid Melanotan 1 peptide offers super-physiological levels of tanning ability.
Research Use: The half-life of Melanotan peptides is very brief. Afamelanotide is being developed in implant form for the ease of use in dermatology. The implant contains a controlled release effecting melanin density for months. Melanotan One is offered in research peptide form (Melanotan).
Lifestyle: Melanocortins have the potential to be the next big thing in lifestyle cosmetic treatment (Viagra, Botox, etc). Melanotan can be appropriately used continuously as well as intermittently.
Recommended Therapy: Intermittent therapy, lasting 10 days (skin type III) to 6 months (skin type I) works well. Take note how long after your Melanotan administration melanin density stays elevated.
Peptide Molecule: Two amino acids present in the bodies natural a-MSH have been changed in production of Melanotan 1 increasing stablity. Melanotan only works when injected subcutaneously.
Amino acid sequence: Ac-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys-Pro-Val-NH2
Clinical Trial: Melanotan is still undergoing clinical trials and has not reached approved status. People use on the pretenses and understanding that it is for research purposes only. Users may suffer from slight nausea and flushing after subcutaneous injection; however it is reported to be mild and pass quickly.
Administration of Research Melanotan
Safe and controlled administration of Afamelanotide for research is done much like that of Melanotan 2. Melanotan One offered as a peptide in a multi-dose sterile vial is desirable. Implants, nasal sprays and pills are not applicable/efficacious at the present time.
Melanotan One is less efficacious than its counterpart Melanotan 2 for achieving a dark tan. Afamelanotide will therefore require 8-10x the dosage to see comparable results. Melanotan One users want minimum side and peripheral effects with a focus on photoprotection. Be patient and prepared through your Melanotan journey.
Melanotan Treatment: Dosing According to Skin Type
Fitzpatrick Skin Type I: 1mg-2mg/day. 100mg total may be necessary to achieve desired color. UV exposure after at least 20mg in system
Fitzpatrick Skin Type II: .75mg-1.5mg/day. 60mg should be sufficient to get color. UV exposure after 10-20mg
Fitzpatrick Skin Type III: .5mg-1mg/day. A sunless tan may be realistic
Fitzpatrick Skin Type IV: Do not use Melanotan
Melanotan Video from Australia
Melanotan can assist the develop a protective tan in users. A natural tan is developed in response to cell damage caused by UV radiation. Ultraviolet rays penetrate the upper layers of the skin, triggering a-MSH, stimulating melanin production. Melanin deposits act as a natural sunblock at the cellular level. Melanotan tanning injections may offer a way to bring upon a safe, cosmetic tan with less damage.
