drtbear1967
Musclechemistry Board Certified Member
Dimethyltrienolone is a hybrid between trestolone and methyltrienolone(methyl tren) and is an extremely potent and toxic steroid. It was first synthesized in 1967 but was deemed too toxic to be brought to market.
Based on its chemical structure there are 3 main sections of which to be aware: 1) the alternating double bonds on carbons 4-5, 9-10, 11-12, found in trenbolone dramatically increase binding affinity to the androgen receptor(and the progesterone and glucocorticoid receptors) and prevents it from converting both to estrogen and DHT. 2) the methyl group on carbon 7alpha prevents this molecule from binding to SHBG(the protein that inactivates sex hormones). 3)the methyl group on carbon 17 prevents inactivation during passage through the gut/liver(as well as increases liver toxicity).
Dimethyltrienolone has a binding affinity to the AR of 1.8x greater than that of testosterone, better than trestolone but slightly lower than tren. It’s binding affinity to the progesterone receptor though is extremely high, 300x greater than testosterone and 4x greater than tren. It’s anabolic activity is about 100x greater than methyltestosterone, but it’s as or more toxic as methyl tren.
DO NOT underestimate its liver toxicity. It also binds very tightly to your mineral/glucocorticoid receptors in a similar fashion to aldosterone. This means that it can inhibit reabsorption of sodium in your kidneys which can throw off your electrolyte balance and interfere with Na/K pump. I haven’t personally used this compound before, but it is around online and I’ve heard of people gaining muscle and “hardening” while using it. It can be taken both orally and IM injection, and doses should probably err on the low side,1mg/d. It’s heavily advised to use strong liver protectant supplements like TUDCA and NAC or Glutathione while taking this compound. It also likely negatively affects your HDL/LDL so use caution there as well. I’m interested to hear any anecdotal feedback from people whom have used this compound.
Based on its chemical structure there are 3 main sections of which to be aware: 1) the alternating double bonds on carbons 4-5, 9-10, 11-12, found in trenbolone dramatically increase binding affinity to the androgen receptor(and the progesterone and glucocorticoid receptors) and prevents it from converting both to estrogen and DHT. 2) the methyl group on carbon 7alpha prevents this molecule from binding to SHBG(the protein that inactivates sex hormones). 3)the methyl group on carbon 17 prevents inactivation during passage through the gut/liver(as well as increases liver toxicity).
Dimethyltrienolone has a binding affinity to the AR of 1.8x greater than that of testosterone, better than trestolone but slightly lower than tren. It’s binding affinity to the progesterone receptor though is extremely high, 300x greater than testosterone and 4x greater than tren. It’s anabolic activity is about 100x greater than methyltestosterone, but it’s as or more toxic as methyl tren.
DO NOT underestimate its liver toxicity. It also binds very tightly to your mineral/glucocorticoid receptors in a similar fashion to aldosterone. This means that it can inhibit reabsorption of sodium in your kidneys which can throw off your electrolyte balance and interfere with Na/K pump. I haven’t personally used this compound before, but it is around online and I’ve heard of people gaining muscle and “hardening” while using it. It can be taken both orally and IM injection, and doses should probably err on the low side,1mg/d. It’s heavily advised to use strong liver protectant supplements like TUDCA and NAC or Glutathione while taking this compound. It also likely negatively affects your HDL/LDL so use caution there as well. I’m interested to hear any anecdotal feedback from people whom have used this compound.
