Exemestane, commonly known by the brand name Aromasin, is a popular aromatase inhibitor (AI) used by bodybuilders during or after anabolic steroid cycles, particularly those involving testosterone. Its primary function is to prevent the conversion of testosterone into estrogen by inhibiting the aromatase enzyme. For bodybuilders, controlling estrogen levels is crucial to avoid estrogen-related side effects such as gynecomastia (enlarged breast tissue), water retention, and fat gain.
When testosterone or other anabolic steroids are used, the body's estrogen levels can increase, leading to hormonal imbalances. Exemestane is often preferred because of its ability to permanently deactivate aromatase enzymes, resulting in a long-lasting reduction of estrogen levels. This makes it particularly useful for those on testosterone-heavy cycles who want to maintain a lean, defined physique without excess water weight or fat accumulation.
Exemestane differs from other AIs, like anastrozole and letrozole, in that it has a steroidal structure, making it less likely to negatively impact cholesterol levels when used in moderate doses. Additionally, it has a reputation for being milder on libido and joint health, issues often exacerbated by estrogen suppression.
Typical dosing for bodybuilders using Exemestane ranges from 12.5 mg to 25 mg every other day, depending on the cycle and individual sensitivity to estrogen. It is often introduced during the cycle or as part of post-cycle therapy (PCT) to help rebalance hormone levels and mitigate estrogen rebound once steroid use is discontinued.
However, bodybuilders must monitor estrogen carefully, as reducing it too much can lead to side effects like fatigue, joint pain, and a decrease in sexual function. Bloodwork is recommended to ensure estrogen levels remain within an optimal range.
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