Fifth week of Epistane and some issues with breast/nipple (Quick Help Please)

[gvnch]

Hello guys, starting new thread because I kindly ask for the quick response. I am into fifth week of my Epistane cycle (1st cycle - epi - 2013, 2nd cycle - hdrol - 2014, 3rd cycle - epi - right now).

I gain about 13 pounds yet, cycle goes pretty well and I had planned another week (overall 6 week cycle). But last 2 days I feel kinda discomfort in my left nipple/breast (little pain when I lie on chest or washing my body/chest in the shower).

Should I screw another (6th) week and start my PCT with Clomid right now? I dont want to have some serious issues! My nipples seems to be fine visually, but those last 2 days making me feared. There is also something hard under that nipple/breat area - (like gland or something) compared to right nipple. It feels weird :/

I have CLOMID and NOLVA on hand, but I only have nolva for my 4 week PCT, not more. What should I do?

Thanks in advance!

 

[Muscle mechanic]

Start pct 6 weeks long to be on orals. Gyno can be triggered in times of liver stress.

 

[Muscle mechanic]

I get nothing in my nipples but ingrown hair and zits from shaving. Are u running any test at all.
6 weeks oral with no testosterone your gyno if present is from shutdown, not epistane because it doesn't covert to estro. As mentioned we need some test to estrogen or gyno can occur.
Anything that causes shutdown by negative feedback can cause us to develop gyno because if our testosterone gets too low then available estrogen even if not high can make unfavorable estro to testosterone ratio and cause gyno. This is same risk going into pct when we stop testosterone so why take that risk while on cycle without testosterone. This is why testosterone is necessary on cycle from normal function even brain function. Gyno can also occur if estro gets too high with testosterone especially in people who have had puberty gyno. Higher rates of estro will feed these tissues

 

[Presser]

Hello guys, starting new thread because I kindly ask for the quick response. I am into fifth week of my Epistane cycle (1st cycle - epi - 2013, 2nd cycle - hdrol - 2014, 3rd cycle - epi - right now).

I gain about 13 pounds yet, cycle goes pretty well and I had planned another week (overall 6 week cycle). But last 2 days I feel kinda discomfort in my left nipple/breast (little pain when I lie on chest or washing my body/chest in the shower).

Should I screw another (6th) week and start my PCT with Clomid right now? I dont want to have some serious issues! My nipples seems to be fine visually, but those last 2 days making me feared. There is also something hard under that nipple/breat area - (like gland or something) compared to right nipple. It feels weird :/

I have CLOMID and NOLVA on hand, but I only have nolva for my 4 week PCT, not more. What should I do?

Thanks in advance!

You need to jump on Nolvadex right away, as this is what will compete with the free floating estrogen to bund to the receptor, so the sooner you get the Nolvadex in you at 40mg daily the better, and then drop down to 20mg daily when you feel the estrogen side effects subside

Im editing this, as I don't know what epistanbe converts to, and I thought this was a traditional estrogen related gyno / itchy puffy nipple issue,

So what does epistane convert to then ?

 

[yellow snow]

You need to jump on Nolvadex right away, as this is what will compete with the free floating estrogen to bund to the receptor, so the sooner you get the Nolvadex in you at 40mg daily the better, and then drop down to 20mg daily when you feel the estrogen side effects subside

Im editing this, as I don't know what epistanbe converts to, and I thought this was a traditional estrogen related gyno / itchy puffy nipple issue,

So what does epistane convert to then ?

Epi is in the same subset as winnie and Var ( DHT based if memory serves me). They are not compounds that don't convert to Estrogen................Not sure why he would be getting gyno issues on a Epi run only.

 

[gvnch]

Im taking dermacrine with it, 4 pumps/day. It may be it?

 

[first blood]

Can it raise prolactin??
I thought Epi was no more after the federal prohormone law was passed??? I cant keep up with these PHs!!!!

 

[yellow snow]

Can it raise prolactin??
I thought Epi was no more after the federal prohormone law was passed??? I cant keep up with these PHs!!!!

No one that I have talked to has ever had issue with Epi and Estrogen/prolactin, but everyones body is different.

Epi got clipped in the 2014 ban, but there were a ton of fire sales before the ban went into effect and I know that many people stashed great hords of thier beloved Epi.

 

[Muscle mechanic]

Yellow snow is correct. Epistane is methyl of an gyno drug breast cancer fighting drug in Japan. Epistane has no affinity to estro or prolactin receptors in way of conversation or stimulation. It is a dht sulfur androgen.
Epistane causes no estrogen or prolactin sides or rebound.
That why I said if he is developing gyno it's from being shutdown and test to estrogen ratio wacked!
Low testosterone to estro ratio can cause gyno.
Oral alone with no testosterone cycles should be kept short 3-4 weeks max but I advise to always have testosterone period.
Start Nolva pct whatever deal. Nolva 40 a day 3-4 then 20 another week or two.
Clomid sure that too.
I did Nolva only pct and clomid Nolva. Prefered Nolva but always did some clomid most of time
Derma is not testosterone and it could covert to estro it's basically topical dhea if I am not mistaken

 

[trekrider215]

I think what mechanic said is right. Test to estro ratio is off. The compound doesnt have to aromatize to cause problems. You guys realize how many different pathways there are that cause gyno? Shit theres still many many that are unknown so it could really be a number of things.

Foe instance look at anadrol. Anadrol can cause gyno and their technically not even sure how. People have a number of guesses but its still uncertain.

 

[Muscle mechanic]

You need to jump on Nolvadex right away, as this is what will compete with the free floating estrogen to bund to the receptor, so the sooner you get the Nolvadex in you at 40mg daily the better, and then drop down to 20mg daily when you feel the estrogen side effects subside

Im editing this, as I don't know what epistanbe converts to, and I thought this was a traditional estrogen related gyno / itchy puffy nipple issue,

So what does epistane convert to then ?

Epistane is dht androgen. Because of its structure it doesn't have ability to aromatase. And yes it is methyl version of breast cancer gyno drug from Japan. AND as we know with masteron and it's methyl brother superdrol and Boldonone and it's methyl brother dbol the methylation adds to anabolic effects and hypertrophy and greatly increases alot of things giving a different affect from parent unmethyl counterpart.
Epistane doesn't convert in our body's into anything estrogenic or progesterone. It is active just like it is, no need to convert to activate androgen receptors and be anabolic.
So it's active with no conversation and it doesn't aromatase or have any progesterone or estro metabolites thru metabolism.

It binds directly to androgen and estrogen receptors, where it acts as an antagonist and am agonist. At least epitiostanol does.

 

[Redbull]

Great answers guys. I've never tried epi but have heard about it quite often over the years, especially back when it was otc. I stick to bread and butter compounds like test e, eq, tren, winni, mesterolone etc. those have all worked well at staying lean and muscular with very few negative sides. Great advice so far. I'm not a huge fan of Nola, as I hear it's a bit harsh on the liver and that's a problem when using orals that are 17aa. It made me a bit moody also. Does anyone like aromasin? I like the suicide deactivation of the aromatace enzyme wich kills it so there's no rebound of circulating estrogen that's floating around when you stop taking it like other anti e's are known for and supposedly doesn't lower igf levels to boot. It can also be used as a pct that raises natty test. Everyone is correct in saying epi doesn't aromatize because the dht chemical structure doesn't allow it to. Some would say it even lowers estrogen. Personally I'm not prone to gyno but had a small lump a year ago under the right nipple and I double my aromasin dose to 20mg daily for a week and that killed it. Best thing is to get rid of it now or it can be permanent. Good luck, keep us posted bro.

 

[Muscle mechanic]

Nolva and clomid should be used in pct because of LH signal, LH is interrupted with AI's like Aromasin, adex and letro. Pct is a time we do not want this at all because LH signals testes to make testosterone. Pct is time for serms. Ai's are meant for cycles and estro maintenance when testosterone levels are normal never during pct. Again Ai's interrupt LH.
Also there is no extra estro available from letro or adex to circulate or a come back at all. Aromasin only causes suicide to aromatase enzymes bound to, by binding so strong to deforms until metabolized.
Adex and letro compete and inhibit in this way. Inhibit by competitively inhibiting. Those enzymes of aromatase that are present and can't aromatase because of competitors (letro and adex) must be metabolized before adex and letro are done with. With orals really easy. With long esters simply reduce letro or adex as a taper in same way half life of long esters are metabolized and excreted. It's only a matter of a day or two after half life over.
Inhibit means to stop no store of of.
Serms bind and block they don't inhibit but should be used during time of pct because estro will get back to normal after coarse and testosterone to estro ratio will prevent gyno. So let's kick up those serms for LH and get that testosterone back.
The liver issue with Nolva or clomid isn't enough to risk not getting testosterone back. Nolva and clomid are sonething that comes with chosing to use gear.

 

[gvnch]

My PCT ends today. There is still something (lump?) near/under my nipple. It is less painful, but I feel it when I putting on my stretchy t-shirt or when I touch it by mistake. Should I take 50mg clomid for this week?