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Fighting Father Time.

drtbear1967

Musclechemistry Board Certified Member
by Matt Weik

There’s no getting around it… Father Time is a bitch. He doesn’t care how nice you are. He doesn’t care how much money you have in the bag. Regardless, we are all going to age. Some of us more gracefully than others, but that youthful appearance you once had in your teen’s and 20’s, you better have some photos because it’s not going to last. So, grab your selfie sticks and start snapping all the photos you want now before Father Time decides to sending things south. The good news from all of this though, is that through intense exercise, we can actually slow down the aging process and science is backing it up.

Throw away the aging creams

Aging creams may work a little, but there’s nothing like good old tossing around the iron, showing the treadmill who’s boss, and getting after it in the gym. This keeps your lean muscle mass in check, body fat under control, and helps keep your skin nice and tight (keeping everything in the places they should be in your body). But, age truly is just a number when your cellular age is in check. When your cellular health is good, it allows your body to function properly and optimally. When cells start dying, morphing, mutating is when adverse effects start becoming apparent and you see your overall health slowly changing and deteriorating. The good news is that researchers are now saying that if you exercise intensely, you might be able to shave off around nine years of your cellular age.


To get a little scientific on you, researchers have looked specifically at telomeres which are the ends of all of our chromosomes. Through our telomeres, scientists can detect our cellular age. If our telomeres are getting smaller, it indicates the aging process. If our telomeres can stay the same size, we can maintain a healthy cellular age. Maintaining their size is not going to come easy. There’s no special diet or pill you can swallow. In order to maintain telomere size, you’re going to need to put in some sweat equity at the gym.



Researchers have looked at telomeres in both active individuals who exercise regularly, as well as those who are sedentary and don’t exercise at all. What they found is that those who exercise regularly with good intensity have longer telomeres than those who don’t exercise at all and sit around all day. Looking at both sides of this spectrum from an appearance standpoint, you can also notice the aging process was a lot nicer to the individuals who engaged in regular exercise whereas the sedentary individuals possessed more body fat and looked noticeably older (skin, face, hair, musculature, cardiovascular output, etc.).

What’s it take to maintain telomere length?

While exercise in general has been linked to improved health and longevity, in order to preserve years on a cellular level, you’re going to need to do some cardio with your weight training. In fact, a fair amount.


In order to save around nine years of life on a cellular level, men are going to need to engage in cardio (such as jogging) for 40 minutes around five days a week. This is to be considered “highly active” according to researchers. Women on the other hand would still need to engage in an activity like jogging five days a week, but they would only be required to hit around 30 minutes each day. Researchers looked at individuals who were following such guidelines for over 30 days in order to see these types of results at a cellular level.



One researcher said, “Just because you’re 40, doesn’t mean you’re 40 years old biologically. We all know people that seem younger than their actual age. The more physically active we are, the less biological aging takes place in our bodies. If you want to see a real difference in slowing your biological aging, it appears that a little exercise won’t cut it. You have to work out regularly at high levels. We know that regular physical activity helps to reduce mortality and prolong life, and now we know part of that advantage may be due to the preservation of telomeres.”



Sources:
1.) Brigham Young University. “High levels of exercise linked to nine years of less aging at the cellular level: New research shows a major advantage for those who are highly active.” ScienceDaily. ScienceDaily, 10 May 2017.
2.) Larry A. Tucker. “Physical activity and telomere length in U.S. men and women: An NHANES investigation.” Preventive Medicine, 2017; 100: 145 DOI: 10.1016/j.ypmed.2017.04.027
 
I am really going to have to dig to find the study, but I thought they have shown where you can replace shorter telomers with new longer telomers after doing fasting.

Almost to the effect that fasting can reverse aging and also can cleans the body of cancer cells.
 
I have read something like that, but I have no idea where it was. If you find it, please post.
 
Wow father time is exact term I use when I describe best way to adjust to age, of course we can slow down the process a bit not can never stop it in its tracks. For the first approx 40 yrs of my life, I had great abs and if there was some fat there, it took a short time of dieting and cardio and presto it was gone, now at 58, getting a six pack takes seemingly forever to get, near perfect diet and lots of cardio and even then they will never look like in my younger days

Also down is strength,it wasnt maybe 7 yrs ago before my nerves got pinched in my left tricep, I was man handling 130lb dumbells for reps on bench press, now half that feels heavy

Last but not least is the lack of alvailable poo tang LOL. What was once easy as falling off a log is now nearly impossible. The few bucks I spent on a couple of drinks at the bar hitting on women, I now spend on cheap porn sites :)

It does suck but at least I'm still vertical!
 
I am really going to have to dig to find the study, but I thought they have shown where you can replace shorter telomers with new longer telomers after doing fasting.

Almost to the effect that fasting can reverse aging and also can cleans the body of cancer cells.


Yes we have a whole bunch of actual studies posted on Telomeres and their effects on aging and how to slow down the process of aging by slowing down the “fraying” of the ends of telomeres, and yep, I know of two studies here offhand that showed the actual reversal, not just slowing down.

IGF-1 was in a couple of the studies showing its effects on telomeres length, and as yellow snow stated, fasting showed effectiveness with telomere length, good memory man! I forgot all abut the fasting one!
 
Wow father time is exact term I use when I describe best way to adjust to age, of course we can slow down the process a bit not can never stop it in its tracks. For the first approx 40 yrs of my life, I had great abs and if there was some fat there, it took a short time of dieting and cardio and presto it was gone, now at 58, getting a six pack takes seemingly forever to get, near perfect diet and lots of cardio and even then they will never look like in my younger days

Also down is strength,it wasnt maybe 7 yrs ago before my nerves got pinched in my left tricep, I was man handling 130lb dumbells for reps on bench press, now half that feels heavy

Last but not least is the lack of alvailable poo tang LOL. What was once easy as falling off a log is now nearly impossible. The few bucks I spent on a couple of drinks at the bar hitting on women, I now spend on cheap porn sites :)

It does suck but at least I'm still vertical!


Hey brutha, let me ask you this, do you still juice regularly? And im talking about a steady stream of testosterone , not all out stacking hormones cycle, but I am simply curious whether or not this is the case for you at this age and your still juicing or not?

I would hope the gear would make it easier to keep lean and abs and such even at 58 years young!


As for the POO Tang as you so eloquently put it lol, Man, I should put some porn sites into my stock portfolio lmao , well thats if I had a stock portfolio lmao but you get the point
 
Survivor, at what age did you get fat, go bald, and limp?? lmao!!!!

Just playing, and well if you are bald, I didnt know it, so sorry! lol, and I know your not fat, and if your watching porn I doubt your limp!

Anyhow, man you been with us here at MuscleChemistry.com almost 14 years man!!! So you joined here what in your early 40’s right? Life was good, and you were posting about loving to be single and banging one nighters if memory serves me correct! You enjoyed the bachelor life more than being tied down to one women , so has that changed???
 
Survivor, at what age did you get fat, go bald, and limp?? lmao!!!!

Just playing, and well if you are bald, I didnt know it, so sorry! lol, and I know your not fat, and if your watching porn I doubt your limp!

Anyhow, man you been with us here at MuscleChemistry.com almost 14 years man!!! So you joined here what in your early 40’s right? Life was good, and you were posting about loving to be single and banging one nighters if memory serves me correct! You enjoyed the bachelor life more than being tied down to one women , so has that changed???
Not bald, but I noticed hair grows everywhere except where it should, ie ears, nostrils etc LOL

I'm far from fat as much as I dramatize, just have some fat on the abs plus I have a diastatis recti where my abs have split making my gut distended

Not that I was tooting my horn but getting laid was so fricking easy yrs ago, I even took for granted and now pulling teeth seems easier. I've had offers from married women at my gym but looking at the wrong end of a gun not option!

To sum it up, I get easily bored w one woman, a few months and I'm thinking I need a change. Hence the constant turnover. That hasnt changed other than I feel past my expiration! A huge part is women in my dating range all have issues as we all hold baggage from previous relationships and most women are very leery of someone like me. Thank God I have a dog!
 
Hey brutha, let me ask you this, do you still juice regularly? And im talking about a steady stream of testosterone , not all out stacking hormones cycle, but I am simply curious whether or not this is the case for you at this age and your still juicing or not?

I would hope the gear would make it easier to keep lean and abs and such even at 58 years young!


As for the POO Tang as you so eloquently put it lol, Man, I should put some porn sites into my stock portfolio lmao , well thats if I had a stock portfolio lmao but you get the point

Yes I still juice prob half the year (actually even off cycle, I still use HRT dosages, nothing insane, test and some decca, 500/200 per wk and yes in the right lighting my abs do show, I still want to compete again sometime in the next yr or so

I was BSing about paying for porn sites, I do all free ones and I never let spanking the monkey control me LOL. What would porn stock look like on the NYSE? XXX? :)
 
This is not the study I was really looking for; there is a much better one out there, but I can't seem to find it. Bottom line is that inflammation is thought of as the "smoking gun" when it comes to Telomere shortening. Fasting has been shown to stop most inflamation in the body...........and so you have to connect the dots, but I know there is a study that connects them for you I just can't find it.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3037593/

This is why a lot of longevity sights promote Inter. fasting, fasting or keto based diets.
 
No way my knees and back could deal with jogging or running. Hell I do go to walk most days. And when it gets cold, sometimes that is all I can do.
 
This is from Pub med showing that DHA ( fish oils) reverse the telomere shortening:


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See comment in PubMed Commons belowJAMA. 2010 Jan 20;303(3):250-7. doi: 10.1001/jama.2009.2008.
[h=1]Association of marine omega-3 fatty acid levels with telomeric aging in patients with coronary heart disease.[/h]Farzaneh-Far R[SUP]1[/SUP], Lin J, Epel ES, Harris WS, Blackburn EH, Whooley MA.
[h=3]Author information[/h]<dl class="ui-ncbi-toggler-slave ui-ncbitoggler ui-ncbitoggler-slave" aria-hidden="true"><dt>1</dt><dd>Division of Cardiology, Room 5G1, San Francisco General Hospital, 1001 Potrero Ave, San Francisco, CA 94110, USA. [email protected]</dd></dl>

[h=3]Abstract[/h][h=4]CONTEXT:[/h]<abstracttext label="CONTEXT" nlmcategory="BACKGROUND">Increased dietary intake of marine omega-3 fatty acids is associated with prolonged survival in patients with coronary heart disease. However, the mechanisms underlying this protective effect are poorly understood.</abstracttext>
[h=4]OBJECTIVE:[/h]<abstracttext label="OBJECTIVE" nlmcategory="OBJECTIVE">To investigate the association of omega-3 fatty acid blood levels with temporal changes in telomere length, an emerging marker of biological age.</abstracttext>
[h=4]DESIGN, SETTING, AND PARTICIPANTS:[/h]<abstracttext label="DESIGN, SETTING, AND PARTICIPANTS" nlmcategory="METHODS">Prospective cohort study of 608 ambulatory outpatients in California with stable coronary artery disease recruited from the Heart and Soul Study between September 2000 and December 2002 and followed up to January 2009 (median, 6.0 years; range, 5.0-8.1 years).</abstracttext>
[h=4]MAIN OUTCOME MEASURES:[/h]<abstracttext label="MAIN OUTCOME MEASURES" nlmcategory="METHODS">We measured leukocyte telomere length at baseline and again after 5 years of follow-up. Multivariable linear and logistic regression models were used to investigate the association of baseline levels of omega-3 fatty acids (docosahexaenoic acid [DHA] and eicosapentaenoic acid [EPA]) with subsequent change in telomere length.</abstracttext>
[h=4]RESULTS:[/h]<abstracttext label="RESULTS" nlmcategory="RESULTS">Individuals in the lowest quartile of DHA+EPA experienced the fastest rate of telomere shortening (0.13 telomere-to-single-copy gene ratio [T/S] units over 5 years; 95% confidence interval [CI], 0.09-0.17), whereas those in the highest quartile experienced the slowest rate of telomere shortening (0.05 T/S units over 5 years; 95% CI, 0.02-0.08; P < .001 for linear trend across quartiles). Levels of DHA+EPA were associated with less telomere shortening before (unadjusted beta coefficient x 10(-3) = 0.06; 95% CI, 0.02-0.10) and after (adjusted beta coefficient x 10(-3) = 0.05; 95% CI, 0.01-0.08) sequential adjustment for established risk factors and potential confounders. Each 1-SD increase in DHA+EPA levels was associated with a 32% reduction in the odds of telomere shortening (adjusted odds ratio, 0.68; 95% CI, 0.47-0.98).</abstracttext>
[h=4]CONCLUSION:[/h]<abstracttext label="CONCLUSION" nlmcategory="CONCLUSIONS">Among this cohort of patients with coronary artery disease, there was an inverse relationship between baseline blood levels of marine omega-3 fatty acids and the rate of telomere shortening over 5 years.</abstracttext>
 
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