Not a fan of secretagogues when you can administer the end result igf-1 directly, however its still one of the better secretagogues among its class and shows elevated igf-1 level in humans with just one dosage for nearly a full day, so below is a quick profile of mk-677 for anyone interested in running a cycle of it if thats all you can get your hands on lol
Ibutamoren or MK677 or GHAR1NE is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and a growth hormone secretagogue. To learn more about Ibutamoren visit What is GHAR1NE?
Ibutamoren or MK677 or GHAR1NE is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin/growth hormone secretagogue receptor (GHSR) and a growth hormone secretagogue. To learn more about Ibutamoren visit What is GHAR1NE?
- Generic/Nonproprietary Name: Ibutamoren
- Developmental Code Names: MK-677, MK-0677, L-163,191
- Trade/Brand Names: GHAR1NE
- Chemical Nomenclature: (R)-1′-(2-methylalanyl-O-benzyl-D-seryl)-1-(methylsulfonyl)-1,2-dihydrospiro[indole-3,4′-piperidine]
- Synonyms: 2-Amino-2-methyl-N-[1-(1-methylsulfonylspiro[2H-indole-3,4′-piperidine]-1′-yl)-1-oxo-3-(phenylmethoxy)propan-2-yl]propanamide
- Molecular Mass/Weight: 528.662 g/mol
- Legal Status: Unscheduled (US)
- Oral Bioavailability: Above 30% (in dogs)
- Biological Half-Life: 4-6 hours (in beagles); IGF-1 levels remain elevated in humans with a single oral dose for up to 24 hours
- Methylated: No (Liver Safe)
- Anabolic/Androgenic Ratio: N/A
- Common Dosages: 10mg to 30mg daily
- Common Cycle Length: 1-3 Months
- Dosing Frequency: 1-2 times daily (Once daily if ‘Cutting’ or ‘Recomping’, Twice daily if ‘Bulking’)
- Dosage Timing: Before Bed (Before Breakfast as well if ‘Bulking’)
- Taking on Empty Stomach/With Food: Empty Stomach (Optimally)
- Sample Cycle: 10/10/10/10/20/20/20/20/30/30/30/30 (in mg/day) {3-Month Cycle}
