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Grapefruit Juice

(N)shape

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Interesting information on Grapefruit Juice....will definitely try this out!

Up Yours, Jamba Juice! My little pamplemousse.
That's what I call my girlfriend when we're getting intimate.
It's French. No matter that it means grapefruit, it sounds sexy and it makes her writhe on the bed sheets like a worm on a hot sidewalk.
Speaking of grapefruit, it's the one fruit juice I keep on hand because I'm a supplement extremist. In other words, I like to maximize the effects of my supplements and there's a good chance that grapefruit juice, or more specifically, an ingredient in grapefruit juice, does just that.
The chemical is called bergamottin and it inhibits the action of an enzyme called cytochrome P-450 from doing its job, which is to break down chemicals into non-active forms. In fact, drinking an 8-ounce glass of grapefruit juice with your supps or meds could increase the amount of active chemical in your bloodstream by fourfold. For the most part, we don't know exactly how many drugs or chemicals are affected by bergamottin, but there are a lot and there's a good chance its involved in breaking down whatever supplement you're currently taking. As an example, taking a Viagra pill with grapefruit juice would likely make your erections last even longer. Of course, if you need to have an erection last more than 4 hours, you're just showing off. Really. :satan: So yeah, I often wash down my supplements with an 8-ounce glass of grapefruit juice.
Conversely, both orange juice and apple juice have been shown to have the opposite effect in that they inhibit various drugs and/or supplements from having their full effect. The negating effect seems to be more "mechanical" than enzymatic in that apple juice and orange juice somehow prevent certain compounds from entering the bloodstream.
As if that isn't reason enough to be careful about drinking apple or orange juice, these juices also wreak havoc on your insulin levels. While whole oranges or apples are great (except when taken at the same times as your prescriptions or supplements), consuming them as juice is an entirely different situation. The glycemic index and/or insulin index of most whole fruit is great, but once you juice them, you make them easily digestible, so much so that the sugars are quickly absorbed, resulting in an insulin surge that's not too different from the one you get from drinking an entire Big Gulp of Pepsi. Grapefruit juice, however, is glycemically "safe" in that it doesn't contain many sugars. Here's my recommendation: Take your prescriptions or supps with water instead of orange juice or apple juice. If you insist on drinking either of those two juices, drink them a full two hours before taking your pills. If, however, you're a supplement kamikaze and what to maximize the effects of your supps, take them with 8-12 ounces of grapefruit juice. I urge you not to do this with your prescription meds, though, as grapefruit juice might raise the level of the drugs in your bloodstream to unsafe levels. If you're a dieter or concerned with your blood sugar for any reason, avoid sweet tasting fruit juices in general and opt for their whole-food counterpart. Speaking of apples, Apple computer founder Steve Jobs named the company after his favorite fruit. After high school, Jobs worked in an apple orchard where he experimented with an all-apple diet, believing it might eliminate his need to bathe. It didn't work.
NUTSACK RATING FOR ORANGE JUICE AND APPLE JUICE:
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CAUTIONARY NUTSACK RATING FOR GRAPEFRUIT JUICE:
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Interesting, I never thought anything about it. I normally take supps with water. I don't care for grapfruit juice, but this might change that. I'm always up for trying something new and this might make a difference. What kind of supps are these for in particular, just any in general?
 
Interesting, I never thought anything about it. I normally take supps with water. I don't care for grapfruit juice, but this might change that. I'm always up for trying something new and this might make a difference. What kind of supps are these for in particular, just any in general?

Yeah really anything you take.
 
Inhibition of the enzyme p-450 and it's "sisters", a-j, have always been a concern in pharmacology. You may have seen the ads on tv about Not drinking grapefruit juice when on statins. Now the BB community can use this to there advantage if the drug/substrate your using is indeed saturating that enzyme, meaning which enzyme is trying to knock it out. Its there job to look at the substrate as a foreign body but once its exhausted the remaining drug gets into the blood-stream. You could use grapefruit juice or another enzyme saturation technique before consuming certain aas "by mouth" to increase it's bioavailability. I will look into further and post back.
 
mos def works. dbol and grapefruit juice is a very important part of a balanced breakfast
 
Inhibition of the enzyme p-450 and it's "sisters", a-j, have always been a concern in pharmacology. You may have seen the ads on tv about Not drinking grapefruit juice when on statins. Now the BB community can use this to there advantage if the drug/substrate your using is indeed saturating that enzyme, meaning which enzyme is trying to knock it out. Its there job to look at the substrate as a foreign body but once its exhausted the remaining drug gets into the blood-stream. You could use grapefruit juice or another enzyme saturation technique before consuming certain aas "by mouth" to increase it's bioavailability. I will look into further and post back.

def let us know what you find out!
 
I love grapefruit and the juice. I just recently tried a Pumello which is the sister of the grapefruit. It is a bit bigger and a little sweeter. Very delicious.
 
I take grapefruit with winnie and it works like mother fucker. And I try it without and don't work as well.
 
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