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Injectable Amino Acids. L-Glutathione, L-Carnitine, D-Aspartic Acid.

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<header class="entry-header" style="margin: 0px; padding: 0px; border: 0px; font-size: 14px; vertical-align: baseline; color: rgb(68, 68, 68); font-family: Arial; line-height: 14px; ">[h=2]The Benefits of Injectable Amino Acids[/h]July 12, 2013

</header>The purpose of this article is merely to educate and entertain the reader. This by no means constitutes medical advice or instruction. Injections of any kind should only be performed by medical professionals, and can lead to serious complications if the user is inexperienced in the proper procedures. It should also be noted that any solution can become contaminated, or may contain impurities that could harm the user, therefore it is highly recommended that our readers abstain from the use of said delivery methods.
Amino acids are essential to life as well as necessary for optimal physical performance. Many amino acids are needed as building blocks to make the protein necessary for muscle growth, and yet many specific amino acids serve other purposes, such as increasing neurotransmitters, triggering muscle protein synthesis, and aiding the liver in detoxification.
For the most part, orally consuming amino acids in the form of protein is a perfectly useful way to meet the needs of the bodybuilder, athlete or health enthusiast. Other times, orally ingesting separate and specific amino acids can be useful to treat certain medical or health conditions. Most of the time, the absorption of orally ingested amino acids is more than adequate to take advantage of that amino acid’s benefits. There are times however, where bypassing the stomach, and delivering the amino acid intramuscularly can be of a great benefit. The reasons for this can vary from absorption issues, degradation in the stomach, or concentration limits. In this article we will pinpoint a few unique amino acids that greatly benefit from this alternative delivery system.
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L-Glutathione

L-Glutathione
Glutathione is the master antioxidant of the body. In the liver, Glutathione is produced to combat the free radicals that are generated during the daily tasks that the liver must perform, such as detoxification and fatty acid metabolism. Orally consuming Glutathione however, is an inefficient means of increasing Glutathione levels in the body. Glutathione gets broken down in the stomach into its ingredients, Glycine, Glutamine and Cysteine. Once this breakdown occurs, these amino acids get swept up in the amino pool along with any other ingested amino acids, and does not lead to directly increased Glutathione levels in the blood. Therefore, a more direct route can be accomplished through administration of a sterile solution of Glutathione, delivered intramuscularly. Doing so will greatly increase the body’s capacity to combat free radicals, quell inflammation and even increase feelings of wellbeing, due to Glutathione’s effect on Dopamine sensitivity in the brain. Glutathione is also used as a skin “whitener”. In large doses, combined with Ascorbic acid, injectable Glutathione will in effect bleach the skin, which some people, especially of Asian descent, can appreciate. Much larger doses are needed to achieve this effect, and would not be advisable for those simply wishing to increase their antioxidant health. A daily dose of 100-200mg is all that is needed for optimal results.
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L-Carnitine

L-Carnitine
L-Carnitine is a very important amino acid used in the breakdown of fat for energy. Increasing L-Carnitine levels above and beyond what one would normally consume from diet has the ability to increase fat burning, even in the presence of carbohydrate. This can be an incredibly beneficial effect, but there are a couple catches. For one, the amount of L-Carnitine one would have to consume orally in order to elicit a benefit would far outweigh the costs, and would most likely lead to stomach upset. L-Carnitine levels are tightly controlled, and the cost of L-Carnitine is not cheap, so eating 5-10 grams of it per day would make it impractical for our purposes. The other catch is that the hormone insulin must be present at the same time as the L-Carnitine levels are increased. Consuming enough L-Carnitine and then enough sugar to elicit the desired insulin response would most likely offset the benefits. Injectable L-Carnitine however, allows the advanced user to bypass the gastric limitations, and dramatically increase blood levels of Carnitine at a fraction of the dose. In addition, advanced users may also combine this injectable amino acid with 1 or 2 IU’s of insulin, to increase the absorption of the L-Carnitine into the cells where it is needed to burn fat for energy. It is not advised by this author that anyone attempt the usage of insulin, because of its very real dangers. However, a small glass of orange juice should provide enough of an insulin spike, shortly after the intramuscularly delivered L-Carnitine enters the bloodstream, in order to elicit the desired response. An initial loading phase of 250-500mg per day is recommended, and thereafter, 100-200mg per day is all that is needed to keep the levels consistently high.
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amino acids diagram

By now many people are already familiar with the benefits of Beta-Alanine. The studies showing enhanced sports performance, delayed fatigue and increased endurance are all undeniable. Beta-Alanine truly is a useful amino acid when it comes to athleticism. But did you know that Beta-Alanine supplementation benefits are really due to an amino acid known as L-Carnosine? Much in the same way that L-Glutathione breaks down in the stomach, so does L-Carnosine. The stomach acids break down L-Carnosine into L-Histidine and Beta-Alanine. Most people with an abundant amount of protein ingestion will have more than enough L-Histidine to build L-Carnosine. But Beta-Alanine is a unique amino acid and really needs to be supplemented in order to see its full benefits. So people have started ingesting several grams of Beta-Alanine preworkout in order to experience the increased endurance and delayed muscle fatigue. But many users of Beta-Alanine complain of a tingling sensation when they ingest it. While some people don’t find it to be a problem, others complain that it is very uncomfortable, similar to the flushing sensation that occurs with Niacin ingestion. Also, if you were to take too much Beta-Alanine, stomach upset and diarrhea can occur. The alternative to this would be to deliver, intramuscularly, a sterile solution of L-Carnosine. Once in the bloodstream, L-Carnosine is left intact and can enter the muscle cells, where it quenches the excess hydrogen ions that build up in muscle tissue, affecting pH and leading to muscle fatigue. A daily dose of 200mg intramuscularly will optimize L-Carnosine levels over a period of a few weeks, at which point the user will begin to notice its benefits.
D-Aspartic Acid
A recent breakthrough in the study of increasing Testosterone reveals that a unique amino acid, D-Aspartic Acid, has the ability to increase steroidogenesis within the Testes. The D isomer of Aspartic Acid, behaves much differently than L-Aspartic Acid. It serves as a catalyst to increase SARP (Steroidogenic Acute Regulatory Protein) which increases steroid production directly within the Testes, while at the same time it also increases Luteinizing Hormone, or LH, which is used by the pituitary to signal the need to increase Testosterone levels. This is literally a two-fold secret weapon in the art of increasing Testosterone levels naturally. So what is the catch? Well, tolerability mostly. Many users of D-Aspartic Acid complain of severe digestive issues and diarrhea. Therefore, in order to increase the solubility, and thus increase the absorption without this issue, some manufacturers have made a Calcium chelated version of D-Aspartic Acid. But alas, some users still report troubles with digestion. A sterile solution of D-Aspartic Acid would surely serve as an effective solution to this digestibility problem. A dosage of 100-200mg per day would be all that is needed to see increased Testosterone levels.
In the pursuit of physical perfection, all methods of administration are considered. In some instances, amino acids are perfectly absorbed and easily utilized by means of oral ingestion. In the case of the above Amino acids, however, it is suggested that in order to maximize the potential for these compounds to deliver the sought-after benefits, intramuscular injection of a sterile solution of these amino acids is possible.
It is important to reiterate that the purpose of this article is merely to educate and entertain the reader. This is by no means advice or constituting medical instruction. Injections of any kind should only be performed by medical professionals, and can lead to serious complications if the user is inexperienced in the proper procedures. It should also be noted that any solution can become contaminated, or may contain impurities that could harm the user, therefore it is highly recommended that our readers abstain from the use of said delivery methods.
 
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