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ALFLUTOP is proven to reach peak therapeutic levels in joints within 2 hours to: Relieve pain and reduce inflammation! Restore synovial fluid lubrication to improve joint movement. Inhibit destructive enzymes that attack the synovial fluid and cartilage. Stimulate cartilage repair by blocking destructive enzymes ALFLUTOP is detected in cartilage and subchondral bone up to 4 days after a single injection. The health of the cartilage is critical to the performance of the joint. Reverse degenerative joint disease to help restore the natural balanced wear and repair cycle within the joint. Proven to relieve symptoms of non-infectious osteoarthritis, ALFLUTOP® is the only natural treatment to stop the destructive disease cycle, stimulate cartilage repair and reverse the joint disease process. Administered intramuscularly, ALFLUTOP® is a potent natural inhibitor that travels to traumatized knee or joints. Extensive studies of ALFLUTOP® have proven it readily passes through the synovial membrane and is taken up into cartilage where it concentrates and accumulates at the site of injury.
Drug Classification: Chondroprotector Active Life: approximately 24-36 hours
Order original ALFLUTOP INJECTIONS
Alflutop is the trademarked name of a product produced by the pharmaceutical company Biotehnos. The Alflutop produced by this company contains sea fish bioactive concentrate, which itself contains low molecular mass peptides, mucopolysaccharides, and amino acids. Also included are trace elements including zinc, copper, sodium, calcium, iron, and magnesium. Most often the compound is packaged in one milliliter amps which each contain ten milligrams of sea fish bioactive concentrate, as well as phenol which possesses anesthetic properties as well as acting as a preservative.
The medical use of Alflutop is primarily for the treatment of degenerative joint disorders such as tendonitis, ankylopoietic spondilitis, bursitis, spinal disc injuries and arthritis-related disorders (1). Obviously these are the same uses that bodybuilders and strength athletes will want to utilize Alflutop for as well. Alflutop works in numerous ways to help stop tissue damage from happening in joints, while also repairing tissues that have already been damaged. This occurs via cartilage regeneration and a reduction in free radical damage within joint tissues. As well, the contents of Alflutop help to inhibit overproduction of hyaluronidase, an enzyme that catalyzes the breakdown of hyaluronic acid in the tissues of the body. Excessive production of this enzyme can lead to serious damage within joints. Alflutop will also help to restore and maintain homeostasis within chondrocytes, the structures responsible for the production and maintenance of the extracellular matrix of cartilage.
Along with the injectable version of Alflutop, Biotehnos also produces a topical ointment as well as a suppository form of the compound. However both of these forms of the drug will of course be less efficient as a delivery method of the compound and less effective. The injectable version of Alflutop is also the more commonly found form of the compound. For these reasons, the majority of users will want to administer the drug via injections.
Use/Dosing
Due to the active life of the compound, frequent dosing is required. For the most part, most users find that injecting one amp, 10mgs sea fish bioactive concentrate or one milliliter in volume, every day or every other day for a period of approximately twenty-one days will bring substantial relief in the majority of their symptoms as they relate to joint discomfort and/or damage. However this protocol has basically been devised by way of anecdotal information passed on from one user to another. In clinical trials the length of administering the drug has ranged from less then seven days to as long as several months. It was found that various lengths of time were needed to treated individuals and these were based on several factors including the amount of damage/trauma that was inflicted upon the joint(s), how well the individual reacted to the drug, and how much physical activity and recuperation methods the individuals used in conjunction with the drug treatment, among others. For this reason, no set standard needs to be adhered to when using Alflutop and the length of use should be determined by the results achieved with the compound.
The injectable version of Alflutop is administered via intramuscular injections. It seemingly does not matter which muscles that the compound is injected into as it will affect all of the joints of the user equally. There is no additional benefit to administering the drug into the area of the injury or trauma. This, along with the frequency of the injections, would allow the user to spread the injections throughout several muscle groups so as not to cause undue irritation to the muscles that the compound is being administered to.
In terms of use for females, it appears that the same dosages can be translated to women as they are for men. No real changes to the volume or frequency of the dosing of the drug need to be made, with no increase of severity or frequency of potential side effects being seen in women.
Like the duration of the administration of the drug, the frequency with which a user chooses to cycle the compound seemingly will not be hindered by side effects either. If one chooses to run Alflutop several times within a short period of time, this appears to be beneficial. In fact in the case of rheumatoid arthritis, this is the protocol for treatment using the drug in many cases (2). However anecdotally users have reported only needing to use the compound once or twice for years at a time and have never had a reoccurrence of their symptoms. Of course, a number of factors could also contribute to this, most notably being that most would not subject themselves to the activity that had caused the initial damage or trauma in the first place.
Risks/Side Effects
From the available research that has thus far been conducted it seems that Alflutop is well tolerated by nearly all subjects that have received it as treatment. It is also important to note that the vast majority of this research has been completed using elderly patients due to the research primarily concerning itself with use of the drug in those individuals who suffer from rheumatoid arthritis, among other conditions. This is important since many of these older patients may suffer from other age related diseases and/or conditions. From the research that has been conducted it appears that Alflutop has had not negative effects on those patients suffering from heart conditions, gastrointestinal distress/diseases or diseases of the thyroid (2, 3). Obviously these findings should also presumably hold true for younger, healthier individuals.
The only real negative side effects associated with the administration of Alflutop are some reports of irritation related to the frequent injections. Some post-injection pain was noted by some patients while others tolerated the frequent injections well. However no major complications related to the injections were reported in the available research and literature related to Alflutop.
References
1. Noskov SM, Fetelego OI, Krasivina IG, Dolgova LN. [Alflutop in local therapy of shoulder periarthritis] Ter Arkh. 2005;77(8):57-60.
2. Svetlova MS, Ignat'ev VK. [Use of alflutop in the treatment of patients with osteoarthrosis] Klin Med (Mosk). 2004;82(6):52-5.
3. Taran AI, Puzanova OG, Lapenko OIe, Sol's'kyi VI, Samoilova SM. [Experience gained with the use of local administration of medicinal remedies in rheumatic diseases] Lik Sprava. 2001 Sep-Dec;(5-6):182-5.
Solution for injection 1 amp. The bioactive concentrate shallow marine fish (sprat (Sprattus sprattus sprattus), whiting Black Sea (Odontogadus merlangus euxinus), Black Sea shad (Alosa tanaica nordmanni), Black Sea anchovy (Engraulis encrassicholus ponticus)) 100 ml.
Excipients: Water d /, and phenol (max. 5 mg / 1 ml).
Clinico-pharmacological group: The drug, which improves the metabolism in cartilage.
Pharmacological action
The drug, which regulates the metabolism of cartilage tissue, chondroprotector. It is a concentrate of bioactive shallow marine fish containing mucopolysaccharides (chondroitin sulfate), amino acids, peptides, ions of sodium, potassium, calcium, magnesium, iron, copper and zinc. Alflutop prevents the destruction of macromolecular structures of normal tissues, stimulates regeneration processes in interstitial tissue and tissue of the articular cartilage, which explains its analgesic action.
Anti-inflammatory effect and tissue regeneration based on the inhibition of hyaluronidase activity and normalization of the biosynthesis of hyaluronic acid. These effects are synergistic and cause the activation of metabolic processes in tissues, particularly cartilage tissue, hindering the processes of degeneration.
Pharmacokinetics
Effects of extract of marine organisms is the combined effect of its active components, so the study of pharmacokinetic properties is not possible.
Statementprimary and secondary osteoarthritis of different localization (including coxarthrosis, gonarthrosis, arthrosis small joints);spondylosis;osteochondrosis.
Dosage regimenThe drug is prescribed for adults.
When poliosteoartroze and osteochondrosis Alflutop injected deep into the / m and 1 ml / day. The course of treatment - 20 injections - 1 injection per day for 20 days.
When a primary lesion of the large joints drug injected into the joint of 1-2 ml in each joint with an interval between injections of 3-4 days.
The course of treatment - 5-6 injections in each joint. Perhaps a combination of V / m and intraarticular injection. The course of treatment is advisable to repeat in 6 months.
Side effectRare: dermatitis, itching, redness, burning sensation at the injection site, short-myalgia. Very rare: anaphylactic reaction. In some cases: transient amplification of pain (when intraarticular injection).
ContraindicationsPregnancyLactation (breastfeeding);childhood;Hypersensitivity to the drug's components.We do not recommend use of the drug in children because of lack of data from clinical studies in this patient.
Cautions In the case of individual intolerance of seafood (sea fish) increases the risk of allergic reactions.
OverdoseSymptoms: in predisposed patients may be allergic reactions, sometimes severe course.
Treatment: removal of preparation, conduct of symptomatic therapy.
Terms and Conditions of storageThe drug should be stored out of reach of children, protected from light at temperature of 15 ° to 25 ° C.
[h=3]Bodybuilders and Powerlifters with joint pain via tendonitis, ankylopoietic spondilitis, bursitis, spinal disc injuries and arthritis-related disorders use Alflutop Injections for Reversing Joint Injury[/h]
Order ALFLUTOP INJECTIONS from authorized
Alflutop is a natural, injectable formula that is reported to be more effective than corticosteroid injections, as it not only reduces inflamation, but encourages repair and regeneration of cartilage and connective tissue. Alflutop has proven effective in clinical trials in degenerative joint disorders (bursitis, tendonitis, and arthritis). Comparable in effect, though different in formula from Adequan, Alflutop is reported to be a miracle drug for joint injuries. Alflutop is manufactured by BIOTEHNOS S.A. Romania.
Description: Each 1ml ampule of Alflutop contains 10 mg sea fish bioactive concentrate (amino acids, low molecular mass peptides, mucopolysaccharides, trace elements: Na, K, Ca, Mg, Fe, Cu, Zn), and maximum 5mg/100ml phenol as preservative.
How it works: Alflutop falls into the group of chondroprotective products having anti-hyaluronidase, anti-inflammatory and analgesic action. Alflutop: inhibits hyaluronidase excess; restores chondrocytes homeostasis in damaged tissues; stimulates regenerative processes at cartilage level; adjusts synovial fluid synthesis; stimulates superoxide dismutase; inhibits occurrence of superoxide free radicals.
Dosing: Intramuscular (IM) injection of 1 amp every day for 3 weeks, for a 21 day cycle, which can be followed up 2 months later. Intra-articular (IA) injection has also shown effective in later-stage clinical trials. 1-2 amps into the joint for 21 days.
Alflutop has an active life of approximately 24-36 hours. The dosing protocols above are just guidelines, and the bottom line is you should continue treatment as long as necessary, if need be. There are no indications of toxicity, or any other negative side effects from Alflutop.
Clinical Trial Results:
The clinical trials have confirmed the efficacy of Alflutop in degenerative articular, post-traumatic pathology and abarticular rheumatism: extremely few adverse reactions; lack of major complications; well tolerated, including the patients sufferring from gastrointestinal, cardiovascular and metabolic diseases; and a favourable ratio of costs and clinical efficacy. The clinical trials showed the therapeutical effect of Alflutop in the treatment of periarthritis, spondiloarthrosis, spinal disc injuries, ankylopoietic spondilitis, Reiter syndrome, and rheumatoid polyarthritis.
Arthritis or joint inflammation is one of the most common group of the diseases affecting millions of people all over the world. The word Arthritis is used by health care providers to describe painful and still joints. Arthritis term include more than 100 different kind of illnesses that affect joints. Arthritis can attack joints all over the body causing swelling, redness and pain. Some types of the arthritis are characterized by short-term pain and swelling. Most types of the diseases are chronic and last for a long period of time.
Arthritis can affect not only joints, but other parts of the body such as ligaments, tendons, bones and muscles. In rare cases it may attack internal organs. As there a many arthritis types healthcare providers classified then in several main categories such as:
Hemorrhagic arthritis
Infectious arthritis (septic arthritis)
Inflammatory arthritis (rheumatoid arthritis)
Noninflammatory arthritis (osteoarthritis)
Noninflammatory arthritis include the following types:
Ochronosis
Acute rheumatic fever
Neuropathic arthropathy
Osteoarthritis
Osteoarthritis is a degenerative joint disease that affects cartilages. In severe cases almost all of the cartilage wear away. Osteoarthritis usually affects hands, neck, knee and lower back. Osteoarthritis symptoms can range from mild pain and stiffen to severe joint pain. Osteoarthritis is common for elderly patients.
Inflammatory category of arthritis include:
Lupus arthritis
Gout
Juvenile rheumatoid arthritis
Rheumatoid arthritis
Spondyloarthropathies including ankylosing spondylitis, reactive arthritides, psoriatic arthritis, enteropathic arthritis.
Rheumatoid arthritis is an autoimmune diseases meaning the immune system mistakenly attacks joints. Rheumatoid arthritis is characterized by inflammation of the joints causing swelling, pain and stiffness. The disease of more common for women than for men. Rheumatoid arthritis can attacks any joints in the organism such as wrists, fingers, elbows, hips, feet, neck and other. Along with joint affection, rheumatoid arthritis can damage heart tissue, muscles, eyes, central nervous system, blood vessels
Gout is one of the most painful arthritis types. Pain occurs pain crystals of uric acid form deposits in the conjunctive tissue. These deposits cause pain, heat, swelling in the joint. Gout attacks usually happens after eating peas, dried beans, shellfish. Also being overweight or drinking much alcohol can make the disease worse. Some of the medications can also provoke gout.
Juvenile rheumatoid arthritis is a diseases that affects joints for more than half a year in children or adolescents under 16 years of age. Juvenile rheumatoid arthritis affects joints causing redness, soreness, pain and can limit motion of the affected parts of the body. According to the latest statistics Juvenile rheumatoid arthritis affect more than 200,000 Americans. Juvenile rheumatoid treatment include drug therapy, exercises and medications. In most cases children completely recover.
Lupus Arthritis or systemic lupus erythematosus is a diseases that affects muscle, skin, joints and in some cases internal organs. Lupus erythematosus is a common disease usually affecting women of childbearing age.
Ankylosing spondylitis is an arthritis disease of the spine cord. Ankylosing spondylitis may result in rigid spine or can affect other body's areas such as hips, shoulders, knee, joints, bones and tendons. In the USA nearly 350,000 are suffering from ankylosing spondylitis at current moment. This disease affect more men than women. In many cases Ankylosing spondylitis causes significant pain that can be relieved only by potent pain killers. Reactive Arthritis Reactive arthritis is an arthritis types that occurs as a result of response to an infection. In most cases this is gastrointestinal or urogenital infection. Reactive arthritis can cause urogenital tract inflammations, joint damage and eyes problems. Treatment is based on drug therapy.
Psoriatic ArthritisPsoriatic arthritis is common for patients with psoriasis. According to the statistics nearly 8% of patients with psoriasis develop psoriatic arthritis and more than 160,000 Americans currently have this disease. Treatment of psoriatic arthritis include: drugs, lifestyle changes as well as routine monitoring and ongoing care.
Enteropathic ArthritisEnteropathic arthritis is another form of arthritis (joint inflammation) that develops as a result of inflammatory bowel disease (IBS). Enteropathic Arthritis is common for people suffering from two major forms of IBS such as ulcerative colitis and Crohn's disease. According to the statistic more than 20% of patients with these diseases can have enteropathic arthritis. The disease usually affects wrists, knees, hips, ankles and elbows. Only 5% of patients will develop joint inflammation in the spine.
[h=2]Arthritis treatment[/h]Reducing and improving joint function, pain relief are the main goals in arthritis treatment. There is no single treatment for arthritis, it depends on severity and arthritis type. But there are some common treatment approaches such as:
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