drtbear1967
Musclechemistry Board Certified Member
theguerillachemist
Very interesting study that compares short vs long esters of testosterone and how it affects peak plasma levels, suppression, and aromatization. This study compares test enanthate, test undecanoate, and test bucilate at equal doses of pure test(20mg/kg of test, adjusted for weight of esters) for 28 weeks. They noticed a few things that most users notice as well: the longer the active life(in this case it was the bucilate, then undecanoate, then enanthate) the more suppression of LH, the higher the estradiol levels, the worse it affected HDL/LDL, and the higher the anabolic effect was.
There seems to be a higher degree of aromatization in longer acting esters, despite the sustained release and overall even levels of androgens(ie no peaks and valleys). This is suspected to also influence suppression of LH/FSH, so there might be a strong relationship between aromatization and suppression. This can be seen in dianabol as well.
There was another paper I read that suggests DHT conversion might also be related to ester length. If a compound aromatizes to a large degree, then it should convert to DHT to a smaller degree. It seems that shorter esters have a greater conversion to DHT vs longer, which anecdotally is observed, and usually cause less suppression vs longer esters, despite the dosage. This was shown prior research. Take home: it seems that longer esters have other properties than just extending the half life of a compound: they affect suppression and estrogen conversion and this should be taken into account when designing protocols. My 2 cents
Very interesting study that compares short vs long esters of testosterone and how it affects peak plasma levels, suppression, and aromatization. This study compares test enanthate, test undecanoate, and test bucilate at equal doses of pure test(20mg/kg of test, adjusted for weight of esters) for 28 weeks. They noticed a few things that most users notice as well: the longer the active life(in this case it was the bucilate, then undecanoate, then enanthate) the more suppression of LH, the higher the estradiol levels, the worse it affected HDL/LDL, and the higher the anabolic effect was.
There seems to be a higher degree of aromatization in longer acting esters, despite the sustained release and overall even levels of androgens(ie no peaks and valleys). This is suspected to also influence suppression of LH/FSH, so there might be a strong relationship between aromatization and suppression. This can be seen in dianabol as well.
There was another paper I read that suggests DHT conversion might also be related to ester length. If a compound aromatizes to a large degree, then it should convert to DHT to a smaller degree. It seems that shorter esters have a greater conversion to DHT vs longer, which anecdotally is observed, and usually cause less suppression vs longer esters, despite the dosage. This was shown prior research. Take home: it seems that longer esters have other properties than just extending the half life of a compound: they affect suppression and estrogen conversion and this should be taken into account when designing protocols. My 2 cents
