Best quality Ostarine available at http://www.musclechemistry.com/
At this stage of development there are no SARMs available on the legitimate pharmaceutical market, although one (Ostarine) has made it into the third and last phase of clinical trials. Luckily, however, legitimate SARMs are available for purchase through various peptide companies on the web. In fact, legitimate Ostarine can be found under the code name MK-2866.
S1 (MK 2866 or Ostarine) is another SARM that displays plenty of promise at promoting lean body mass. It is extremely potent, has a long half life, and displays no androgenic effects. This means it won’t cause any secondary “masculine” side-effects. S-1 is purely anabolic like Anavar, something I know women would love to hear especially if they are looking to build muscle without virilization (masculine side effects). It binds strongly to the androgen receptor, but without the side effects normally associated with high levels of testosterone or other compounds. It shows considerable properties as a muscle hardening agent just slightly less than those of S4. It\’s ability to cause fat loss means it can be used on a cutting cycle and can be stacked effectively with fat burners.
S1 has displayed a real ability to help heal those with debilitating injuries and to speed up injury recovery. The beneficial effects on recovery make medical use highly appealing. An added benefit is you get the great recovery without all the negative changes to cholesterol, blood pressure, prostate, heart or any other organs the way anabolic steroids do.
Of the currently studied SARMs, S1 showed in successful phase II clinical trials to significantly increase the lean body mass (LBM) and physical performance of men and women with cancer cachexia who got S1 as opposed to a placebo. Men and women who got S1 had a reduction in serum lipids and a favorable change in LDL to HDL ratios. These results indicate that S1 has can potential help improve bone mass in the elderly.
Do SARMs suppress natural testosterone production or NOT?
It would take more than 70mgs of S4 and 30mgs of S1 a day to have the SARM compete with one’s own natural testosterone production. In rats, at these high dosages, SARMs even suggest potential application for male contraception as they would cause reactions in the body that would lower sperm count. (Endocrinology. 2004;145:5420–5428.)
In this study below, SARMs are being used as a replacement for Testosterone Replacement Therapy.
Currently available testosterone replacement therapy options are largely restricted to injectable or skin delivery formulations of testosterone. Injectable testosterone leads to above normal blood levels right after an injection and below normal levels just before the next injection. Skin patches do provide a better blood level profile of testosterone, but skin irritation and daily application still limit the usefulness and acceptability of this form of therapy. Oral preparations of Testosterone such as fluoxymesterone and 17a-methyltestosterone are not currently used due to concerns about liver toxicity.
The discovery of SARMs will provide the opportunity to develop medications that can be taken orally and have the same benefits of androgen therapy without all the above mentioned adverse side effects.
I think that it is safe to say that doses as high as 50mgs of S4 or 10mgs of S1 will not do anything to the hypothalamic–pituitary–gonadal axis HTPA while promoting beneficial effects like enhancing protein synthesis, building muscle tissue and enhancing lean body mass. (Read about HTPA in the EliteFitness.com forums! )
Since they are not suppressive to natural testosterone production, can SARMs be used as a bridge in between anabolic steroid cycles?
A bridge is means using an anabolic agent that will not suppress natural testosterone production while preserving and adding to the muscle gains from your completed steroid cycle and before you begin your next steroid cycle. A bridge between cycles is usually anywhere from 4-12 weeks depending on your goals. Everyone’s opinion on bridges varies, some may feel it is a waste, others feel it can be the only smart way to cycle. For the serious bodybuilder, a bridge is a must since many bodybuilders would have used a suppressive androgenic anabolic steroid to make gains meaning they would find themselves with little natural testosterone production. That is where SARMs come in; preferably S-1 (mk 2866) as it is virtually non-toxic and has a faster response in creating an anabolic environment. Athletes find that no more than 5mgs of S1 or 10mgs of S4 used during your bridge is all that is needed to maintain your gains and even add additional muscle between steroid cycles.
Best quality Ostarine available at http://www.musclechemistry.com/
Can SARMs be stacked with anabolic steroids during a steroid cycle?
S-1 can be used on cycle as well especially since its touted for its fast acting anabolic capabilities. So if you want to still keep toxicity to minimum while on cycle, S-1 would be in your best interest for your needs. If you choose to run S-4 on cycle 50-100mgs will do great on maximize gains. Now if you should choose S-1 during your cycle, 20mgs would be sufficient but you could go up in dosage if needed to maximize your gains. And YES, you can use both on cycle to really tear it up during your cycle, strength would go up quite substantially.
At this stage of development there are no SARMs available on the legitimate pharmaceutical market, although one (Ostarine) has made it into the third and last phase of clinical trials. Luckily, however, legitimate SARMs are available for purchase through various peptide companies on the web. In fact, legitimate Ostarine can be found under the code name MK-2866.
S1 (MK 2866 or Ostarine) is another SARM that displays plenty of promise at promoting lean body mass. It is extremely potent, has a long half life, and displays no androgenic effects. This means it won’t cause any secondary “masculine” side-effects. S-1 is purely anabolic like Anavar, something I know women would love to hear especially if they are looking to build muscle without virilization (masculine side effects). It binds strongly to the androgen receptor, but without the side effects normally associated with high levels of testosterone or other compounds. It shows considerable properties as a muscle hardening agent just slightly less than those of S4. It\’s ability to cause fat loss means it can be used on a cutting cycle and can be stacked effectively with fat burners.
S1 has displayed a real ability to help heal those with debilitating injuries and to speed up injury recovery. The beneficial effects on recovery make medical use highly appealing. An added benefit is you get the great recovery without all the negative changes to cholesterol, blood pressure, prostate, heart or any other organs the way anabolic steroids do.
Of the currently studied SARMs, S1 showed in successful phase II clinical trials to significantly increase the lean body mass (LBM) and physical performance of men and women with cancer cachexia who got S1 as opposed to a placebo. Men and women who got S1 had a reduction in serum lipids and a favorable change in LDL to HDL ratios. These results indicate that S1 has can potential help improve bone mass in the elderly.
Do SARMs suppress natural testosterone production or NOT?
It would take more than 70mgs of S4 and 30mgs of S1 a day to have the SARM compete with one’s own natural testosterone production. In rats, at these high dosages, SARMs even suggest potential application for male contraception as they would cause reactions in the body that would lower sperm count. (Endocrinology. 2004;145:5420–5428.)
In this study below, SARMs are being used as a replacement for Testosterone Replacement Therapy.
Currently available testosterone replacement therapy options are largely restricted to injectable or skin delivery formulations of testosterone. Injectable testosterone leads to above normal blood levels right after an injection and below normal levels just before the next injection. Skin patches do provide a better blood level profile of testosterone, but skin irritation and daily application still limit the usefulness and acceptability of this form of therapy. Oral preparations of Testosterone such as fluoxymesterone and 17a-methyltestosterone are not currently used due to concerns about liver toxicity.
The discovery of SARMs will provide the opportunity to develop medications that can be taken orally and have the same benefits of androgen therapy without all the above mentioned adverse side effects.
I think that it is safe to say that doses as high as 50mgs of S4 or 10mgs of S1 will not do anything to the hypothalamic–pituitary–gonadal axis HTPA while promoting beneficial effects like enhancing protein synthesis, building muscle tissue and enhancing lean body mass. (Read about HTPA in the EliteFitness.com forums! )
Since they are not suppressive to natural testosterone production, can SARMs be used as a bridge in between anabolic steroid cycles?
A bridge is means using an anabolic agent that will not suppress natural testosterone production while preserving and adding to the muscle gains from your completed steroid cycle and before you begin your next steroid cycle. A bridge between cycles is usually anywhere from 4-12 weeks depending on your goals. Everyone’s opinion on bridges varies, some may feel it is a waste, others feel it can be the only smart way to cycle. For the serious bodybuilder, a bridge is a must since many bodybuilders would have used a suppressive androgenic anabolic steroid to make gains meaning they would find themselves with little natural testosterone production. That is where SARMs come in; preferably S-1 (mk 2866) as it is virtually non-toxic and has a faster response in creating an anabolic environment. Athletes find that no more than 5mgs of S1 or 10mgs of S4 used during your bridge is all that is needed to maintain your gains and even add additional muscle between steroid cycles.
Best quality Ostarine available at http://www.musclechemistry.com/
Can SARMs be stacked with anabolic steroids during a steroid cycle?
S-1 can be used on cycle as well especially since its touted for its fast acting anabolic capabilities. So if you want to still keep toxicity to minimum while on cycle, S-1 would be in your best interest for your needs. If you choose to run S-4 on cycle 50-100mgs will do great on maximize gains. Now if you should choose S-1 during your cycle, 20mgs would be sufficient but you could go up in dosage if needed to maximize your gains. And YES, you can use both on cycle to really tear it up during your cycle, strength would go up quite substantially.
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