drtbear1967
Musclechemistry Board Certified Member
TB500 is a peptide fraction of the protein Thymosin beta4, which is released in times of healing and inflammation. TB500 main mechanism is its ability to regulate Actin-a cell building protein that is present in every cell. By upregulating Actin, your body can now increase cell proliferation cell migration. It also helps promote wound healing, and has been shown to build new blood vessels/endothelial factors, increase keratinocyte migration and increased collagen deposition and muscle fiber.
It has has been shown to downregulate inflammatory chemokines(white blood cell attraction) and has even been shown to promote cell survival. There are not a lot of human studies on this peptide at the moment, but all the animal data seems promising, not to mention the tons of anecdotal evidence for healing. There have even been reports of men regrowing lost hair and gray hair turning darker. There is an animal study showing hair follicle development so this is plausible.
As for the dosing protocol, it's seems to work best by using a loading phase, 4-6 weeks at 4-8mg per week split up into 2mg subQ injections(TB500 is systemic). This can be followed by a maintenance phase of 2-4mg every 2 weeks, again in 2mg doses. It really depends on the severity of the injury and bodyweight to determine an exact protocol for you. It seems to work best on ligament and tendon injuries, but there is evidence for repairing heart damage following a heart attack. This is best stacked with BPC-157 at 500-1000mcg a day (on an empty stomach). Worth noting, there have been studies showing increased cancer cell proliferation with TB500, but only in pre existing subjects.
It has has been shown to downregulate inflammatory chemokines(white blood cell attraction) and has even been shown to promote cell survival. There are not a lot of human studies on this peptide at the moment, but all the animal data seems promising, not to mention the tons of anecdotal evidence for healing. There have even been reports of men regrowing lost hair and gray hair turning darker. There is an animal study showing hair follicle development so this is plausible.
As for the dosing protocol, it's seems to work best by using a loading phase, 4-6 weeks at 4-8mg per week split up into 2mg subQ injections(TB500 is systemic). This can be followed by a maintenance phase of 2-4mg every 2 weeks, again in 2mg doses. It really depends on the severity of the injury and bodyweight to determine an exact protocol for you. It seems to work best on ligament and tendon injuries, but there is evidence for repairing heart damage following a heart attack. This is best stacked with BPC-157 at 500-1000mcg a day (on an empty stomach). Worth noting, there have been studies showing increased cancer cell proliferation with TB500, but only in pre existing subjects.
