big in vegas
MuscleChemistry Registered Member
[h=1]Hold on to your hats, You wont believe this new 2017 published study! on Testosterone effects over 3 years in older adult makes!
Apparently When Men Are given Testosterone gel They outperform their studied counterparts who were given a placebo. Not just outperform, but significantly greater in exercise, muscle mass, and power.
Oh my Gosh , who knew?[/h]
[h=4][/h][h=1]
Effects of Testosterone Supplementation for 3 Years on Muscle Performance and Physical Function in Older Men.[/h]
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Apparently When Men Are given Testosterone gel They outperform their studied counterparts who were given a placebo. Not just outperform, but significantly greater in exercise, muscle mass, and power.
Oh my Gosh , who knew?[/h]
[h=4][/h][h=1]
Effects of Testosterone Supplementation for 3 Years on Muscle Performance and Physical Function in Older Men.[/h]
Storer TW[SUP]1[/SUP], Basaria S[SUP]1[/SUP], Traustadottir T[SUP]2,[/SUP][SUP]3[/SUP], Harman SM[SUP]2,[/SUP][SUP]4[/SUP], Pencina K[SUP]1[/SUP], Li Z[SUP]1[/SUP], Travison TG[SUP]1,[/SUP][SUP]5[/SUP], Miciek R[SUP]6,[/SUP][SUP]7[/SUP], Tsitouras P[SUP]2,[/SUP][SUP]8[/SUP], Hally K[SUP]1[/SUP], Huang G[SUP]1[/SUP], Bhasin S[SUP]1[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h][h=4]Context:[/h]Findings of studies of testosterone's effects on muscle strength and physical function in older men have been inconsistent; its effects on muscle power and fatigability have not been studied.
[h=4]Objective:[/h]To determine the effects of testosterone administration for 3 years in older men on muscle strength, power, fatigability, and physical function.
[h=4]Design, Setting, and Participants:[/h]This was a double-blind, placebo-controlled, randomized trial of healthy men ≥60 years old with total testosterone levels of 100 to 400 ng/dL or free testosterone levels <50 pg/mL.
[h=4]Interventions:[/h]Random assignment to 7.5 g of 1% testosterone or placebo gel daily for 3 years.
[h=4]Outcome Measures:[/h]Loaded and unloaded stair-climbing power, muscle strength, power, and fatigability in leg press and chest press exercises, and lean mass at baseline, 6, 18, and 36 months.
[h=4]Results:[/h]The groups were similar at baseline. Testosterone administration for 3 years was associated with significantly greater performance in unloaded and loaded stair-climbing power than placebo (mean estimated between-group difference, 10.7 W [95% confidence interval (CI), -4.0 to 25.5], P = 0.026; and 22.4 W [95% CI, 4.6 to 40.3], P = 0.027), respectively. Changes in chest-press strength (estimated mean difference, 16.3 N; 95% CI, 5.5 to 27.1; P < 0.001) and power (mean difference 22.5 W; 95% CI, 7.5 to 37.5; P < 0.001), and leg-press power were significantly greater in men randomized to testosterone than in those randomized to placebo. Lean body mass significantly increased more in the testosterone group.
[h=4]Conclusion:[/h]Compared with placebo, testosterone replacement in older men for 3 years was associated with modest but significantly greater improvements in stair-climbing power, muscle mass, and power. Clinical meaningfulness of these treatment effects and their impact on disability in older adults with functional limitations remains to be studied.
[h=4]TRIAL REGISTRATION:[/h]ClinicalTrials.gov NCT00287586.
Copyright © 2017 by the Endocrine Society
[h=3]Author information[/h]
[h=3]Abstract[/h][h=4]Context:[/h]Findings of studies of testosterone's effects on muscle strength and physical function in older men have been inconsistent; its effects on muscle power and fatigability have not been studied.
[h=4]Objective:[/h]To determine the effects of testosterone administration for 3 years in older men on muscle strength, power, fatigability, and physical function.
[h=4]Design, Setting, and Participants:[/h]This was a double-blind, placebo-controlled, randomized trial of healthy men ≥60 years old with total testosterone levels of 100 to 400 ng/dL or free testosterone levels <50 pg/mL.
[h=4]Interventions:[/h]Random assignment to 7.5 g of 1% testosterone or placebo gel daily for 3 years.
[h=4]Outcome Measures:[/h]Loaded and unloaded stair-climbing power, muscle strength, power, and fatigability in leg press and chest press exercises, and lean mass at baseline, 6, 18, and 36 months.
[h=4]Results:[/h]The groups were similar at baseline. Testosterone administration for 3 years was associated with significantly greater performance in unloaded and loaded stair-climbing power than placebo (mean estimated between-group difference, 10.7 W [95% confidence interval (CI), -4.0 to 25.5], P = 0.026; and 22.4 W [95% CI, 4.6 to 40.3], P = 0.027), respectively. Changes in chest-press strength (estimated mean difference, 16.3 N; 95% CI, 5.5 to 27.1; P < 0.001) and power (mean difference 22.5 W; 95% CI, 7.5 to 37.5; P < 0.001), and leg-press power were significantly greater in men randomized to testosterone than in those randomized to placebo. Lean body mass significantly increased more in the testosterone group.
[h=4]Conclusion:[/h]Compared with placebo, testosterone replacement in older men for 3 years was associated with modest but significantly greater improvements in stair-climbing power, muscle mass, and power. Clinical meaningfulness of these treatment effects and their impact on disability in older adults with functional limitations remains to be studied.
[h=4]TRIAL REGISTRATION:[/h]ClinicalTrials.gov NCT00287586.
Copyright © 2017 by the Endocrine Society
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