I started 40mcg on the 5th. I am over 40 with shoulders of a 90 year old. Years of power type lifting and wrestling. I’m looking to try this as way to regain some use of my shoulders again. I’ve tried just about everything over the last couple years. Var used to work for me, when I could get it. I know every one thinks I’m nuts but it worked wonders for me. Anyway, I ‘applied’ the igf for the first 10 days in more healthy areas, to see what to expect from applications. I had no problems, no pain, nothing. So on the 15th tried it in my shoulders (ops I mean delts) That was a very long night. I live with pain as most of us do. This was a few steps above the norm. Any one else try and apply in an area that is beat up from years of abuse? Is it worth trying again? Other than the shoulders I have had no issues. Have not notice much of anything else to this point. I will continue at 40mcg and will report back. Thanks.