Tag: Drugs on WADA
Top Drugs on WADA Watchlist Athletes Must Look Out For in 2022
In a bid to promote the integrity of sports, the World Ant-Doping Agency (WADA) has prohibited the manufacture, supply, and use certain substances. These substances have been found to boost an athlete’s performance beyond their natural capabilities, thus disadvantaging other athletes who are not using the substances. Most of these drugs are hormone boosters and are readily available in the streets where the public can have access at affordable prices. The crackdown on illegal substances has driven most of its manufacturers out of the market by revoking their licenses or prosecution. However, some manufacturers and suppliers have found a way of beating the system and continue to produce and supply the substances under clandestine programs. Moreover, athletes are the biggest victims of their shady operations since doping does not only ruin careers but also interferes with the athletes’ health long-term.
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Regulatory bodies such as WADA have categorized prohibited substances using certain criteria such as chemical composition and severity of their effects. Additionally, there are prohibited methods WADA has outlined for athletes to avoid at all costs. Without further delay, here is the updated list of prohibited substances and methods as outlined on WADA’s official website.
Anabolic Androgenic Steroids (AAS)
Boldenone
Drastanolone
Epitestosterone
7-Keto DHEA
Androstenediol
Gestrinone
Fluoxymesterone
19-Norandrostenediol
Epiandrosterone
Desoxymethyltestosterone
Calusterone
7a-hydroxy-DHEA
1-Testosterone
Androstanolone
Androstenedione
Dehydrochlormethyltestosterone
Ethylestrenol
Formebolone
Furazbol
Bolasterone
Mestanolone
Epi-dihydrotestosterone
Drostanolone
Clostebol
4-hydrotestosterone
Danazol
Anabolic Agents
Quinbolone
Oxabolone
Stenbolone
Trenbolone
Tibolone
Mibolerone
Norboletone
Nandrolone
Metribolone
Mesterolone
Metenelone
Methylchlostebol
Methyldienelone
Tetrahydrogestrinone
Testosterone
Stanozolol
Oxandrolone
Oxymestronone
Metribolone
Methandriol
Methylchostebol
Metandienone
Norclostebol
Norethandrolone
Prasterone
Oxymetholone
Clenbuterol
Zeranol
Zilpaterol
Peptides Hormones
Transforming growth factor beta signaling inhibitors such as sotatercept
Innate repair receptor agonists such as EPO and CEPO
Erythropoietin receptor agonists such as EPO and Depo.
GITA inhibitors
Hypoxia-Inducible factor activating agents such as cobalt and vaadaadugstat.
Growth hormone releasing factors such as GHRH, GHS, GHRPs, Examorelin, among others.
Growth Factors and Modulators
Fibroblast growth factors (FGFs)
Platelet-derived growth hormone (PDGF)
Insulin-like growth factor (IGF-1)
Thymosin and its derivatives
Heptocyte growth factor (HGF)
Vascular endothelial growth factor (VEGF)
Mechano growth factor (MGF)
Beta-2 Agonists
Vilanterol
Terbutaline
Fenoterol
Salbutamol
Arformoterol
Formoterol
Tulobuterol
Reproterol
Fenoterol
Higenamine
Indacaterol
Salmeterol
Tretoquinol
Levosalbutamol
Olodaterol
Procaterol
Note: There are exceptions to the use of Beta-2 agonist. For instance, inhaled salbutamol should not exceed 600 micrograms over eight hours starting from any dose. Additionally, inhaled formoterol, salmeterol, and vilanterol must not exceed 54, 200, and 25 micrograms respectively over 24 hours.
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Hormone and Metabolic Modulators
Testolactone
Letrozole
Exemestane
Androsta-1,4,6-triene-3,17-dione
2-androstenol
2-androstenone
Anastrozole
Formestane
Aminoglutethimide
4-androstene-3,6,17-trione
Cyclofenil
Raloxifene
Ospemifene
Tamoxifen
Clomifene
Bazedoxifene
Fulvestrant
Activin A-neutralizing antibodies
Activin receptor IIB competitors
Myostatin inhibitors such as myostatin binding proteins and antibodies
Activators of the AMP-activated protein kinase
Insulin and insulin-mimetics
Trimetazidine
Meldonium
Diuretic and Masking Agents
Plasma expanders
Desmopressin
Probenecid
Amiloride
Canrenone
Bumetanide
Acetazolamide
Chlortalidone
Etacrynic acid
Thiazides
Indapamide
Metolazone
Prohibited Methods
WADA prohibits the manipulation of blood and blood components. This includes the addition of foreign red blood cells to the blood circulating in the body. It also prohibits athletes from introducing any form or quantity of homologous, autologous, and heterologous blood in their bodies. Athletes are not allowed to boost oxygen delivery to certain parts of the body by artificially altering oxygen uptake and transportation. This is usually done by introducing modified haemoglobin products and other perfluorochemicals. However, they’re allowed to boost oxygen uptake though inhalation. Finally, the regulatory body does not condone any form of intravascular manipulation of the blood and its components through chemical or physical means.
WADA collects samples from suspected cases regularly for analysis. In that case, athletes are prohibited from tampering with or manipulating the samples collected for purposes of analysis. The control body has cited sample substitution and adulteration as the most common tampering methods their officers face. Athletes can use specific chemicals for medical and other purposes other than performance enhancement. However, it forbids intravenous infusions or injections of less than 12 hours for does above 12 ml.
Gene and cell doping are another malpractice among athletes that has drawn the attention of the sports watchdog. It has been found that some participants are using nucleic acid or its analogues to alter genome sequences, thus giving them added advantage when competing. They’re advised to restrain themselves from engaging in gene editing, transfer, and silencing because it will inevitably put them on the wrong side of the law.
Prohibited Stimulants
Prolintane
Furfenorex
Fencamine
Adrafinil
Modafinil
Norfenfluramine
Fenetylline
Crotetamide
Fenproporex
Cocaine
P-methylamfetamine
Mesocarb
Bromantan
Amfetamine
Prenylamine
Clobenzorex
Lisdexamfetamine
Cropropamide
Fenfluramine
Mephentermine
Phendimetrazine
Amiphenazole
Fonturacetam
Benzylpiperazine
Octapamine
Selegiline
Cathine
Ephedrine
Etamivan
Strychnine
Etilefrine
Pemoline
Cathinone
Meclofenoxate
Etilamfetamine
Isometheptene
Sibutramine
Methylphedrine
Fenbutrazate
Pentetrazol
Tuaminoheptane
Nikethamide
Oxilofrine
5-methylhexan-2-amine
3-methylhezan-2-amine
4-fluoromethylphenidate
4-methylpentan-2-amine
Phenethylamine
Epinephrine
Methylnedioxymethamphet-amine
Phenpromethamine
Pseudoephedrine
Propylhexedrine
Narcotics
Pethidine
Oxycodone
Methadone
Morphine
Diamorphine
Buprenorphine
Fentanyl
Pentacocine
Hydromorphone
Nicomoprphine
Dextromoramide
Cannabinoids
WADA has made it clear that it prohibits the use of all cannabinoids by athletes, whether they’re synthetic or natural. That includes all substances contained in cannabis and its products. Additionally, products that contain some levels of THC or those that mimic it are prohibited in totality. Cannabidiol is the only cannabis-related substance that has not been banned by WADA.
Glucocorticoids
Fluocortolone
Mometasone
Prednisone
Cortisone
Hydrocortisone
Triamcinolone
Prednisolone
Deflazacort
Circlesonide
Budesonide
Flunisolide
Methylprednisolone
Fluticasone
Betamethasone
Dexamethasone
Triamcinolone acetonide
Beta Blockers
Bunolol
Labetalol.
Nadolol.
Timolol.
Oxprenolol.
Sotalol.
Esmolol.
Bisoprolol.
Pindolol.
Propranolol.
Betaxodol.
Acebutolol.
Atenolol.
Carvedilol.
Metipranolol.
Celiprolol.
Carteolol.
Nebivolol.
Alprenolol.
Overall
From the WADA list of prohibited substances and methods above, it is evident that most drugs we use every day are mentioned. However, it is important to note that not all the drugs mentioned are harmful to your body. For instance, cannabis and its products are mentioned but we use it every day for medical and recreational purposes. WADA is only trying to create a level playing field for all athletes. That way, every win will be deserved and a lose may not be contested by participants who feel cheated. Similarly, some substances are detrimental to your health and must be avoided at all costs, whether you’re a competitive athlete or not.