Welcome to The Morning Dose, your one-stop shop for all things peptides, TRT, fitness, anti-aging, and everything in between.
We’ve got a great newsletter for you today, so grab some coffee, and get ready to learn.
In this week’s edition of The Morning Dose:
Reader Q&A
Peptide Spotlight: CJC-1295
The FDA is Coming for Our Peptides… Again
Research Spotlight: Low Muscle Mass Increases Mortality
Let’s inject this.
First time reading? I’m Matt, and this is The Morning Dose. Every week, our team scours hundreds of sources to bring you need-to-know news and insights you won’t find elsewhere. All in 5 minutes.
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Reader Q&A
Want us to answer your questions? Hit reply, ask us your training, nutrition, or peptide questions, and we’ll choose one to answer in each edition of The Morning Dose.
We can’t guarantee an answer, but we’ll pick an interesting question each week to share. And if you want to speak with us directly about your burning questions, our coaching team is available for consultations.
Here are this week’s questions, along with answers from Coach Daniel Louwrens.
“I’ve seen peptides available for injection, oral dosing, and even nasal sprays. Which is the best delivery method? I’d prefer to avoid injections if possible, but I’ll do it if that’s the best way.”
The research makes it very hard to say which is best, as we don’t have much data comparing the various methods of delivery.
Instead, we have to think about this logically. If we think about injections, we understand we’re bypassing the skin and digestive system, straight into the muscle.
With an oral dose, the peptides go through the digestive system and may be altered as they pass through your body, losing some bioavailability.
With a nasal spray, absorption rates can be affected by the size of your nose.
Injections are the most reliable, as you bypass most of the body’s defense systems and don’t have to worry about absorption problems, so it’s the only way to know exactly how much you’re getting.
“Are there any peptides that help with cognitive function? My wife and I are in our mid-fifties, and we’re looking for peptides for optimal brain health and overall anti-aging peptides.”
Absolutely! I’d always start with a base of growth hormone, which is the master of all peptides. Try to get a prescription from a pharmacy if possible, to ensure the purest source.
If you can’t access growth hormone, you can use growth hormone secretagogues, which stimulate natural production. Things like CJC-1295 and Ipamorelin are great options to increase growth hormone production!
The foundation of cognitive health is proper sleep, so if you struggle to get quality sleep, you may want to consider adding delta sleep-inducing peptide, or DSIP.
If you want to ask your questions, hit reply to this email, and your question may be chosen for an upcoming email.
As always, your information is completely anonymous with us – we’ll never share your name or identifying information!
Peptide Spotlight: CJC-1295
Since it was mentioned in this week’s Q&A, let’s take a closer look at CJC-1295, one of the most popular peptides.
CJC-1295 belongs to a family of peptides called growth hormone (GH) secretagogues. These peptides cause a natural increase in GH levels, rather than injecting pure HGH.
As pharmaceutical-grade, physician-prescribed HGH is quite expensive, GH secretagogues provide an affordable alternative.
Users still receive the same benefits from the elevated GH: a reduction in body fat, an increase in lean body mass, improved skin health, and many other anti-aging benefits.
While this peptide can cause some side effects, like vertigo, increased body temperature, and mood swings, it’s generally safe to use at low doses and is often stacked with other secretagogues, like Ipamorelin.
As always, please consult with your physician before taking any peptides, as all peptides can have side effects.
The FDA is Coming for Our Peptides… Again
In an earlier edition of The Morning Dose, we reported that the FDA issued a warning against semaglutide from compounding pharmacies. They banned HCG compounding back in 2020, and now, they want to shut down even more peptides.
For those who aren’t aware, there are compounding pharmacies out there that will fill custom medication prescriptions from physicians out there.
Doctors can make all kinds of custom medications and order them from the compounding pharmacy, while your local grocery store pharmacy is limited to commercial medications in standard doses.
Anti-aging doctors regularly use compounding pharmacies to fill prescriptions for custom peptide blends, TRT blends, weight-loss drugs, and more…
But the FDA wants to shut this down.
If anyone has been using TRT for a while along with HCG from a specialized clinic, you likely remember when compounding pharmacies were forced to stop making HCG back in 2020, and suddenly the prices skyrocketed, if you could get it at all.
Now, the FDA has just added a whole list of peptides to their category 2 due to “significant safety risks,” which severely limits their availability to prescribing physicians.
This list includes BPC-157, CJC-1295, Ipamorelin, Melanotan II, TB-500, and many others.
In other words, these peptides are now very difficult, if not impossible to get prescribed by a physician.
So if your doctor has been prescribing these peptides to you, that may soon come to a grinding halt, if it hasn’t already.
Clearly, these peptides have all kinds of benefits, and we’re hopeful the FDA changes its mind.
In the meantime, you may need to turn to research labs that manufacture and sell peptides. Do your research, find one you trust, and look for regular lab testing.
We recommend BioTechPeptides.com – you can use the code BP10 for 10% off your order.
Research Spotlight: Low Muscle Mass Increases Mortality
We’ve long known about the benefits of exercise.
Sure, it’s not always fun, but it’s far too often skipped, especially when our schedules get busy. It’s worth prioritizing.
Many people are spending thousands of dollars optimizing their health, yet ignore one of the core components of longevity.
Once again, research has shown that exercise may actually improve your lifespan, specifically, resistance training to avoid age-related muscle loss.
At the most recent Annual Meeting of the European Association for the Study of Diabetes, a research team shared their newest findings on the impacts of muscle loss and mortality.
“The researchers found that individuals with diabetes and low muscle mass have a higher risk for cardiovascular disease mortality and all-cause mortality.” –Medical News Today
We’re not surprised, and frankly, this is something you should be focused on regardless of whether you have diabetes.
Muscle mass declines with age, and regular strength training is the key to preventing muscle loss.
Muscle can improve insulin sensitivity, helping your body appropriately handle carbohydrates, and regular weight training is one of the best ways to strengthen your joints and increase bone density.
Regardless of your health goals, regular strength training should always be a weekly habit to optimize your health and longevity.
-The Morning Dose
PS – Have questions or suggestions? Hit reply and let us know what you think.
Disclaimer: This content is NOT medical advice. The information included in these emails is intended for entertainment and informational purposes only.F