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  1. Masher59

    PT-141 Bremelanotide

    PT-141 PT-141 or Bremelanotide is the generic term for a research peptide being studied for its possible use in helping to improve sexual dysfunction in both men (erectile dysfunction or impotence) and women (sexual arousal disorder). PT-141 was developed from the tanning peptide Melanotan 2...
  2. Iron Game

    Testosterone for treating depression.

    Testosterone for the treatment of depression: A comprehensive review. Abstract: Testosterone is the primary male sex hormone, 2009 will mark the 104th anniversary of the term “hormone” named by Ernest Starling. Although the biological effects of testosterone were known for many centuries, the...
  3. Iron Game

    The History of Synthetic Testosterone

    Testosterone has long been banned in sports as a performance-enhancing drug. This use may soon be accepted in medicine alongside other legitimate hormonal therapies (by John M. Hoberman and Charles E. Yesalis ) On June 1, 1889, Charles Edouard Brown-Sequard, a prominent French physiologist...
  4. Dean Destructo

    Behavioral characterization of non-copulating male mice

    Non-copulating (NC) males are those animals that do not mate in spite of repeated testing with sexually receptive females. They have been observed in several species including rats and mice. The present experiment was designed to perform a detailed behavioral characterization of NC male mice...
  5. Iron Game

    Testosterone "makes men less susceptible to inflammatory diseases".

    It was long known that men suffer more rarely from inflammatory diseases than women, but now a new research has found how sexual hormones play an important role in this. They found that testosterone makes men less susceptible to inflammatory diseases and allergies than women. “In a series of...
  6. Iron Game

    German researchers declare testosterone based male birth control a failure

    An international trial of a male birth control injection has failed due to its serious side effects, the professors overseeing the German implementation of the test announced Monday. The trial, conducted by the World Health Organization (WHO) and CONRAD, a non-profit organization aimed at...
  7. Dean Destructo

    Melatonin and male reproduction.

    Melatonin is a neurohormone secreted by the pineal gland whose concentrations in the body are regulated by both the dark-light and seasonal cycles. The reproductive function of seasonal breeding animals is clearly influenced by the circadian variation in melatonin levels. Moreover, a growing...
  8. Dean Destructo

    Adverse effects of common medications on male fertility.

    <abstracttext>An increasing number of patients require long-term medication regimens at a young age, but the adverse effects of medications on male reproduction are often inadequately considered, recognized and investigated. Medications can affect male reproduction through central hormonal...
  9. Dean Destructo

    Testosterone and Adult Male Bone

    Androgens and estrogens influence skeletal development and maintenance in males. However, the relative contributions of the circulating sex steroid hormones that originate from testicular/adrenal secretion versus those produced locally in bone via intracrine action require further elucidation...
  10. Dean Destructo

    Brdt Bromodomains Inhibitors; Modern Male Contraceptive

    Compared to efficient and secure female contraception, a vasectomy and condoms are the only options for men. The choice of male contraceptive methods is limited, so contraception mainly rests on the shoulders of women. Several concepts are considered: testosterone administration--inhibiting...
  11. Iron Game

    Latest research study shows Testosterone does NOT cause prostate problems

    Testosterone Replacement Treatment may now be officially recommended to men suffering "male menopause" in light of new findings, doctors say. The breakthrough findings were released at the start of Britain's first ever Andropause Awareness Week, in time for a gathering of scientists and...
  12. Iron Game

    History of the development of Anabolic Steroids

    By: Dan Gwartney, MD Few people know of the current state of anabolic androgenic steroids (AAS); it may be rarer still to find someone with knowledge of the history of anabolic steroids. Sadly, the best texts on the subject directly from the pioneers are difficult to locate as they have been...
  13. Dean Destructo

    Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility.

    Physiol Rev. 2016 Jan;96(1):55-97. doi: 10.1152/physrev.00017.2015. Male Reproductive Disorders and Fertility Trends: Influences of Environment and Genetic Susceptibility.Skakkebaek NE1, Rajpert-De Meyts E1, Buck Louis GM1, Toppari J1, Andersson AM1, Eisenberg ML1, Jensen TK1, Jørgensen N1, Swan...
  14. Iron Game

    The Truth about Low Dose Cycles

    written by BASK8KACE If you've read some of my posts on other boards, you probably already have seen that I advocate suggesting low doses for beginners. Why jump into 600mg per week of test as a first or second cycle when it is highly likely you will get great gains using 200-300mg (in initial...
  15. Iron Game

    Vitamin E protects testes while taking steroids

    Vitamin E protects testes while taking steroids While on a course of steroids, taking extra vitamin E [upper structural formula shown below] reduces damage caused to the testes. An animal study published 6 years ago in Andrologia by animal scientists from Harran University, Vitamin E...
  16. Presser

    Estrogen is Very Important in Nitrogen retention & muscle building through its role in the Production Of Growth Hormone & Insuline-Like Growth Factor

    How and why Estrogen is as important a hormone as any in building muscle, recover, healing, growth hormone and IGF-1 production! Testosterone is the primary substrate in the male body for the synthesis of estrogen (etradiol), the principal female sex hormone. Estrogens presence may be unusual...
  17. Iron Game

    Muscles on the Strip: Las Vegas Gearing Up for Olympia Weekend

    In September, Las Vegas will once again turn into bodybuilding central when Joe Weider's Olympia Fitness & Performance Weekend rolls into town on September 16, 2016. The highlight of the event will, of course, be the 2016 Mr. Olympia contest. Phil Heath, who captured his 5th straight title last...
  18. 3J

    a very good review of anabolic steroids and male infertility

    This was a pubmed article i found on anabolics and its effects on male fertility... i recommend anyone who decides to go on cycle or trt read this, esp if you are planning on having children. Be smart about the choices you make. Its your body, you only get one! Abstract What’s known on the...
  19. Iron Game

    Anabolic Androgen Steroid (AAS) Receptor Sensitivity:

    Anabolic Androgen Steroid (AAS) Receptor Sensitivity: by Dan Gwartney, MD In the real world, or at least as real as it gets in the gym, bodybuilders and lifters have long been aware that some people explode on fairly moderate anabolic steroid dosages, while others struggle to justify the...
  20. Iron Game

    Clenbuterol, Fat Loss Aid

    Clenbuterol, Fat Loss Aid Clenbuterol is a stimulant drug prescribed outside the United States for asthmatics. In some ways, it works like ephedrine as a "beta-2 agonist" (i.e., dilates the airways and reduces constrictive wheezing). However, unlike ephedrine (which is out of the body in a...
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