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by Patrick Arnold A considerable chunk of my work day is always spent answering people’s questions about prohormones and steroids. Of course, one of the biggest concerns people have is about estrogen and estrogen related side effects. Right behind that however are questions about DHT. It seems...

<header class="entry-header" style="box-sizing: border-box; font-family: Roboto, sans-serif; font-size: 16px; line-height: 26px;">DHT (Dihydrotestosterone)</header>The main androgen secreted by the testes is of course testosterone. However, in most of the body, the androgenic signal is not...

The physiological androgens testosterone and 5α-dihydrotestosterone regulate the development and maintenance of primary and secondary male sexual characteristics through binding to the androgen receptor (AR), a ligand-dependent transcription factor. In addition, a number of nonreproductive...

Life is balance. The teeter-totter on school playgrounds is a perfect example of how things tend to gravitate toward equilibrium unless some outside force acts. A pair of equal-weight first-grade children would soon get bored and wander off unless they start leg pressing the teeter-totter up and...

How and why Estrogen is as important a hormone as any in building muscle, recover, healing, growth hormone and IGF-1 production! Testosterone is the primary substrate in the male body for the synthesis of estrogen (etradiol), the principal female sex hormone. Estrogens presence may be unusual...

Which is better for fat loss? Resistance training or Aerobic's? For years, aerobic training has been synonymous with fat loss. Once your waistline has gone over the limit and your trousers become too tight, the first thing that will come to your mind is aerobic training. How many times have...

Red Blood Cell Increase Leads to Increased Endurance. Here's some more info: Blood Doping – Physical Performance Enhancements and Potential Harmful Side-Effects Colby Phillips ...Energy for exercise comes from the oxidation of fuel, and capacity to consume oxygen is a limiting factor for...

RAD-140 New S.A.R.M. Reviewed Mike Arnold S.A.R.M’s, or selective androgen receptor modulators, as they are called, have become all the rage among pharmaceutical researchers looking to cash in on the next-generation of low-risk anabolics. With a potentially high degree of selectivity for...

DOMS, Inflammation, and Muscle Growth Why Your Muscles Get Sore: Exercise and Delayed Onset Muscle Soreness by Matt Perryman If you've ever done any kind of hard activity, you've had sore muscles. It's inevitable, even to couch potatoes. If you exercise on any regular basis, it's guaranteed...

by Mike Arnold Over the last 10 years, the grim reaper has visited our community more times than I care to remember. In fact, more post-millennium professional bodybuilders have died in their 30’-40’s than in the previous 3 decades combined. While it is true that not all of these deaths can be...

RAD-140 is indeed very interesting. First, as to terminology. An “agonist” is a molecule which activates a receptor. A full agonist, at high enough concentration in the blood or test medium, can achieve 100% effect from the receptors. A partial agonist, also called a weak agonist, can only...