How to choose right syringe filters and filter membranes

[El Pezidente]

Hi guys,


The texture of syringe filters include Nylon, PVDF, PTFE, MCE, CA, Glass Fiber, PP, PES.


When choosing the texture of syringe filters, we need to consider pore diameter, chemical resistance( if can resist all carrier oils and solvents), oil-based or water-based solution, and etc.


Here are the pore diameter of common syringe filters.


Pore diameter:
Nylon, PVDF, PTFE, MCE, CA, PP, PES: 0.22um, 0.45um
Glass Fiber: 0.7um, 1.2um


Here are some common questions we enounter when choosing proper syringe filters?
1. Is it necessary to have a 0.22 um to have a sterile solution or the 0.45 um gives acceptable results concerning the dangers of bacteria ?
2. What is the average filtering time per 100ml oil-based injections and water-based injections? What carrier oil you use?
3. Warming your injection will make filtering much easier. What is the filtering time difference between warmed and unwarmed oil?
4. Which membrane are the best for a steroid based solution? Oil-based and water-based.


Here is the chemical resistance chart of Whatman syringe filters/filter membranes.


Nylon PVDF PTFE MCE CA Glass Fiber PP PES
Benzyl Alcohol LR R R R LR R R NR




R=Resistant
LR=Limited Resistance
NR=Not Resistant




I would like to answer the above questions with my shallow expertise.
1. 0.22 um is used for sterilizing-grade filtration. Literally speaking, getting rid of bacterials. 0.45um is used for clarification filtration and pre-filtration. Always stick to
0.22 um though more time-consuming. I want to correct my words in the past posts.
4. Just considering the pore diameter, Glass Fiber is out of the game. Then comes to chemical resistance, Nylone, CA, and PES are out of the game too. So the rest
options might be good for use: PVDF, PTFE, MCE, PP. But deeper consideration is: would these syringe filters not be eaten by other solvents(like BB, EO, guaiacol,
PS80), even carrier oils? As far as I know, sesame oil eats PES.


My provisional conclusion is: 0.22 um of PVDF, PTFE, MCE, PP are good for use. But it is a open proposition.


All MC bros are welcome to anwser these questions. Always glad to discuss this with all you guys.




PS:
Nylon: Nylon
PVDF: Polyvinylidene Fluoride
PTFE: Polyfluortetraethylene
MCE: Mixed Cellulose Ester
CA: Acetate Cellulose
Glass Fiber: Glass Fiber
PP: Polypropylene
PES: Polyether Sulfone

Believe it or not the Foxx 0.45 PES can take 250mg (1% BA, 10% BB) enanthate in GSO or MCT oil like a it's a big gulp. I wouldn't rely on 0.22 but you'd probably be OK with it. I am not sure why nylon isn't rated higher. For chemikaze's using Guiacol or other potent solvents I used to say PVDF but Millipores bottle unit's IMO have been shitty whereas I have beaten the living dogshit out of Zapcaps and they overperform by 50%+ .
PTFE filters strong acids and & aldehydes.

 

[BkMothaFuka]

The Millipore ones I have used int he past have all off sudden started clogging and its super hard to keep pumping

 

[Userat204]

I use whatmam zap cap CR and nothing else best filters ever. They don't screw on but work great. Use a 45 neck glass media bottle.

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[Tailor]

zapcap cr coming in 0.45um. Is it enough for proper filtration?

 

[Muscle mechanic]

zapcap cr coming in 0.45um. Is it enough for proper filtration?

.45 is considered sterile.
And I am pretty sure most labs use It!
Anyway they say certain virus's can get thru but u don't get I viral abscess only bacteria ones!
Ba will stop production of viruses and they will not be preserved in your vial to become active. They need a host or they die!
But still baking is done with. 45 and the time saved u can bake a cake and lots of stuff while oven us hot!

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[chihuahua]

.45 PVDF sterile Whatman.. Done. If you want to be there all day by all means use the .22. I have yet to come across anyone that has gotten an infection from using a .45. Maybe I'm just lucky when comes to filtering. Good luck

 

[PezBolic]

hmm, I literally just bought a few more nylon filters because I seemed to have read all over the web that was preferred.

I didn't quite understand the way you worded it. You said nylon and pes are out because of chemical resistance. What does that mean? That solvents will eat the filter?

These links are compatibilty charts. There are some things missing but you will get an idea. PES is only ok for a prefilter of a very low BA/BB mix. Nylon is the best overall but prefiltering ie a 0.8 or 1.0 micron nylon syringe filter or 47mm membrane (all found in nylon) are ideal if you want to save your filters. I am going to put a post dispel a lot of myths are things people are doing wrong.

http://sevierlab.vet.cornell.edu/resources/Chemical-Resistance-Chart-Detail.pdf
http://www.treborintl.com/content/chemical-resistance-chart

Pics (right) Millipore 0.22 micron PVDF STERIVEX. Prefiltered and using the veterinary syringe NOBODY SHOULD OR NEED TO USE A CAULK GUN. That syringe is $8 at any tractor supply or online. Guys, You've gotta prefilter. It is easier and saves you money. You can't be a cheapskate.

 

[PezBolic]

One thing about this thread. I am fairly certain the ratings against Benzyl Alcohol,BB, Acetone,ect is if the ENTIRE sample is that chemical. I can see this from empirical experience. Nylon needs to be 'nylon 66' made material. It works. However, if one were filtering pure solvents PTFE is the only way to go. EO is falling way out of favor as far as I can tell and guiacol works but it stinks and it comes thru skin pores. Whomever is content with using 0.45 micron pore size remember staph aureus can routinely get thru this size. The link below even says 0.22 membranes can have this happen. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2896367/
Oil and BA help a lot. Water is like a petri dish. Theoretically 0.1 micron filters would be as good as one could get but that is not practical. You have to be a search engine magician to find them in a syringe filter of a suitable membrane.

 

[newwave]

Quick question

Can someone explain the differences between inlet outlet female male?

Getting some filters and they have female inlet and male outlet. Are these OK to use? I have PDVF 0.22um 33mm and PES 0.10um 33mm both sterile. The first used for oils and the second for amino acids in water.

Thanks

 

[PezBolic]

Using a 90mm (or whatever diameter the membrane is) nylon or PVDF filter membrane ON top of say the 0.22 micron PES will do the dirty work and should fix this problem. Unless already pre-filtered a 0.65-0.45 micron size will do it. Just look at the drip. If it rolls through like the Wermacht thru Poland you are kind of screwed. PES ones that sell for $13 are not a good buy. Maybe if they are $5 each in a box of 12 (fire sale price) they can be useful. If someone is making a bunch of bacteriostatic water or filtering GSO, CSO, or MCT oil. It' s not a problem. Just my $0.02.

 

[PezBolic]

Quick question

Can someone explain the differences between inlet outlet female male?

Getting some filters and they have female inlet and male outlet. Are these OK to use? I have PDVF 0.22um 33mm and PES 0.10um 33mm both sterile. The first used for oils and the second for amino acids in water.

Thanks

I think that is the normal way. The syringe goes in, or screws to the 'female' top and the male has the 'dong' for lack of a better term at the end. PES should be fine for aminos. It just depends on what the preservative/anti-microbial is (parabens, ect) .

 

[PezBolic]

zapcap cr coming in 0.45um. Is it enough for proper filtration?

Cellulose Acetate is not anywhere near ideal. If you had a 70mm membrane set on top of it that would help a lot. That's the size they come in. Hard to come across unless you look quite a bit. And never use Nalgene Nylon filters. They suck and Foxx bioscience is weak too (membrane is not very thick). At least with those they take 90mm membranes. Watch the flow rate. It should be a steady drip (quick) not like sucking Pepsi through a straw.

 

[PezBolic]

Hi guys,


The texture of syringe filters include Nylon, PVDF, PTFE, MCE, CA, Glass Fiber, PP, PES.


When choosing the texture of syringe filters, we need to consider pore diameter, chemical resistance( if can resist all carrier oils and solvents), oil-based or water-based solution, and etc.


Here are the pore diameter of common syringe filters.


Pore diameter:
Nylon, PVDF, PTFE, MCE, CA, PP, PES: 0.22um, 0.45um
Glass Fiber: 0.7um, 1.2um


Here are some common questions we enounter when choosing proper syringe filters?
1. Is it necessary to have a 0.22 um to have a sterile solution or the 0.45 um gives acceptable results concerning the dangers of bacteria ?
2. What is the average filtering time per 100ml oil-based injections and water-based injections? What carrier oil you use?
3. Warming your injection will make filtering much easier. What is the filtering time difference between warmed and unwarmed oil?
4. Which membrane are the best for a steroid based solution? Oil-based and water-based.


Here is the chemical resistance chart of Whatman syringe filters/filter membranes.


Nylon PVDF PTFE MCE CA Glass Fiber PP PES
Benzyl Alcohol LR R R R LR R R NR




R=Resistant
LR=Limited Resistance
NR=Not Resistant




I would like to answer the above questions with my shallow expertise.
1. 0.22 um is used for sterilizing-grade filtration. Literally speaking, getting rid of bacterials. 0.45um is used for clarification filtration and pre-filtration. Always stick to
0.22 um though more time-consuming. I want to correct my words in the past posts.
4. Just considering the pore diameter, Glass Fiber is out of the game. Then comes to chemical resistance, Nylone, CA, and PES are out of the game too. So the rest
options might be good for use: PVDF, PTFE, MCE, PP. But deeper consideration is: would these syringe filters not be eaten by other solvents(like BB, EO, guaiacol,
PS80), even carrier oils? As far as I know, sesame oil eats PES.


My provisional conclusion is: 0.22 um of PVDF, PTFE, MCE, PP are good for use. But it is a open proposition.







PS:
Nylon: Nylon
PVDF: Polyvinylidene Fluoride
PTFE: Polyfluortetraethylene
MCE: Mixed Cellulose Ester
CA: Acetate Cellulose
Glass Fiber: Glass Fiber
PP: Polypropylene
PES: Polyether Sulfone

The context needs to be made. Resistance is relative. Keep in mind this is referencing SRTAIGHT BA, BB, ect. so even the wimpy PES can handle some things in small amounts but I would avoid altogether. Nylon: It gets a bad rap. It's a good membrane as long as them membrane is adequately thick
.
PDFE - there are hydroPHILIC and hydroPHOBIC versions- that being said this is for filtering PURE SOLVENTS. You can use it but I can tell you this much, use it in syringe filters and get out a fucking sundial.

PVDF: All purpose, hydrophilic, and is good. Nylon is cheaper , and for the most part is perfectly ok. For a syringe use PVDF gets the nod.

MCE: I'm not sold on it. Have no feedback.
AS ALWAYS DO RESEARCH AND PREFILTER. DON'T SPEND $6.00 TO FILTER 30CC OR RUIN YOUR THUMBS. I have no idea why I see dudes wasting $$ using 0.22 only. YES-use them, but find a larger pore and you will have a much easier time. Spend a little to save a lot of money and effort. Hint -ebay.

 

[PezBolic]

Sorry about the gigantic font. 47mm filters and the 300ml beaker top with metal clamps and receiver cost maybe $50. Find some and if you want sterile then use the syringe filters. For the cost of a 1.5 cfm 1/4 HP pump ($90 @ Harbor Freight) you are set. MCT oil is 1/2 the viscosity of GSO and by the gallon it's $40. I dont know who would need that much so start cooking with it and putting it in shakes.

 

[gymjunkie38]

The nylon zapcap says its chemical resistant. Isnt that chem resistant what we want? Or no?

- - - Updated - - -

It jusy got here the mothet fucker doesnt have threads. You gotta be shitting me. It says its for 45mm glass, but it doesnt even screw on. Wtf

Those seal too the media bottle with vacuum once you pull a vacuum it will suction too the top of the media bottle bro.

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[HULK1972]

What is an inorganic filter membrane at .22 microns what type it's it?
nouler Juler 1000Ml Filter Unit Vacuum Unit + 50X 0.22Um Inorganic Filter Membrane for Filtration of Aqueous Solution Amazon.com: nouler Juler 1000Ml Filter Unit Vacuum Unit + 50X 0.22Um Inorganic Filter Membrane for Filtration of Aqueous Solution: Sports & Outdoors

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[1_whocares]

I am brand new to home brew. I have finally gotten all of the things I think I need. (I had to wait a good bit to get the glass rods for stirring)

I have syringe filters. They are supposed to be good up to 100mls, they are the 25mm size.

After continually reading I am concerned. Can I actually end up rupturing the membrane in the filter if I try to push it through with to much force? They are PVDF filters. The "large" volume syringes I was going to use to push the oil through with are veterinary syringes without the luer lock, they are just bare nipples.

I know the oil should be hot to aid filtering speed.

So my question is, can I rupture the membrane if I push the plunger too hard or am I worried about nothing?

Second question, is using veterinary syringes to push the oil through the filter a bad idea because it doesn't have to lock part of the luer lock? Will I end up creating so much pressure that I push the filter off of the nipple? (The only syringes I have that have the locking ring that the filter can screw into are 3cc, but I have probably over 300.)

Basically all my concerns are around how much pressure is going to be required to filter the finished oil.
Am I worrying over nothing? It wouldn't be the first time.

 

[thx]

I am brand new to home brew. I have finally gotten all of the things I think I need. (I had to wait a good bit to get the glass rods for stirring)

I have syringe filters. They are supposed to be good up to 100mls, they are the 25mm size.

After continually reading I am concerned. Can I actually end up rupturing the membrane in the filter if I try to push it through with to much force? They are PVDF filters. The "large" volume syringes I was going to use to push the oil through with are veterinary syringes without the luer lock, they are just bare nipples.

I know the oil should be hot to aid filtering speed.

So my question is, can I rupture the membrane if I push the plunger too hard or am I worried about nothing?

Second question, is using veterinary syringes to push the oil through the filter a bad idea because it doesn't have to lock part of the luer lock? Will I end up creating so much pressure that I push the filter off of the nipple? (The only syringes I have that have the locking ring that the filter can screw into are 3cc, but I have probably over 300.)

Basically all my concerns are around how much pressure is going to be required to filter the finished oil.
Am I worrying over nothing? It wouldn't be the first time.

Those filters aren't made to filter oil. So you'll never be able to push 100ml of oil through those filters.

Oil should NEVER be hot. I never go above 40 degrees Celsius.

Yes you can rupture the membrane or crack the actual syringe filter if too much pressure is applied and/or the oil is hot.

My advice is to use luerlock syringes.

 

[BkMothaFuka]

What media botttle and bottle top filter should k buy for a test C and prop? I can’t use syringe filters, had success with bottles tops like almost 20 years ago but then had less the next few times and was getting clogged.

The stuff with nebulizers etc are over my head with out out a a video and don’t want to spend hours melting plastic. What are my options, I. Plan to use only bb and ba and which ever oil. Not sure I like EO melting stuff and then going in my body with or with out whatever it melted. Dropped some on my computer years ago and it ate the paint right off it.

 

[Presser]

What media botttle and bottle top filter should k buy for a test C and prop? I can’t use syringe filters, had success with bottles tops like almost 20 years ago but then had less the next few times and was getting clogged.

The stuff with nebulizers etc are over my head with out out a a video and don’t want to spend hours melting plastic. What are my options, I. Plan to use only bb and ba and which ever oil. Not sure I like EO melting stuff and then going in my body with or with out whatever it melted. Dropped some on my computer years ago and it ate the paint right off it.

as long as you heat the carrier oil to 250 degrees and use ba and bb, you should be fine without the filter . USP grade oil like grape or mct works best