been using 25 gauges for the longest, time. I get assistance from a female companion for the hard to reach areas for aspiration and delivery. I bought 23's this time so its easier on her small fingers to push the fluid through, went to pierce and was like GOT DAMN THAT THING IS HUGE.... I've always been a baby with doing injections myself not pain just the anxiety and I still haven't outgrown it haha. Thought I would think out loud for a moment.