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thank you,i will look into that.i know its available where i stay but dont know if their pricey.
my natural testlevel is on the low side(340 something)so i was thinking before of 100mg testo e and 50mg tren e a week,but you say its better with igf-1 lr3?
i posted them in the sticky thread in our steroid and bodybuilding articles forum, sorry!
lol
For most I don't think they are needed. However if you want to use t3 I recommend a t3/t4 combo for optimal results and fewer side effects. Something like 15-20mcg t3 and 100mcg t4 should be gtg.
</abstracttext>https://www.ncbi.nlm.nih.gov/pubmed/808728/Recovery of pituitary thyrotropic function after withdrawal of prolonged thyroid-suppression therapy.
Vagenakis AG, Braverman LE, Azizi F, Portinay GI, Ingbar SH.
Abstract
<abstracttext>The pattern of thyrotropin secretion was analyzed in seven euthyroid women, before and after withdrawal of long-term thyroid hormone, by serial measurements of thyroid 131l uptake, serum thyroxine, tri-iodothyronine, and thyrotropin concentrations, and the response to thyrotropin-releasing hormone. During exogenous hormone administration, 131l uptake was suppressed, and serum thyrotropin concentrations before and after administration of thyrotropin-releasing hormone were undetectable. After withdrawal of exogenous hormone, thyrotropin secretory function was transiently impaired, as indicated by undetectable basal thyrotropin concentrations together with absence of response to thyrotropin-releasing hormone, and subsequently by normal values of basal thyrotropin concentration and normal responses to releasing hormone while serum thyroxine and tri-iodothyronine concentrations were subnormal. Decreased thyrotropin reserve persisted for two to five weeks. Detectable values of serum thyrotropin (less than 1.2 muU per milliliter) and a normal 131l uptake usually occurred concurrently in two to three weeks. Serum thyroxine concentration returned to normal at least four weeks after hormone withdrawal.
http://press.endocrine.org/doi/abs/10.1210/jcem-41-1-70?journalCode=jcem#sthash.uCopg3WC.dpufNormal increments of T4 and T3 after TRH occurred at 19 ± 5 and 22 ± 6 days, respectively.
http://www.thyroiduk.org.uk/tuk/research/Thyroid-Medications.htmlEffects of evening vs morning thyroxine ingestion on serum thyroid hormone profiles in hypothyroid patients
Conclusions:
l-thyroxine taken at bedtime by patients with primary hypothyroidism is associated with higher thyroid hormone concentrations and lower TSH concentrations compared to the same l-thyroxine dose taken in the morning. At the same time, the circadian TSH rhythm stays intact. Our findings are best explained by a better gastrointestinal uptake of l-thyroxine during the night.